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theadder
Posted on: Jun 10 2015, 03:54 PM


Group: Member
Posts: 5,264

Hi there,

From the USPTO yesterday a granted patent

http://patft.uspto.gov/netacgi/nph-Parser?...u&RS=ACN/au

United States Patent 9,050,415

Shetty , et al. June 9, 2015

Devices for targeted delivery of therapeutic implants

Abstract

An implant delivery syringe includes a barrel, a plunger assembly, and a barrel adapter. A barrel adapter mountable to a syringe barrel includes a barrel tip, needle retraction mechanism, needle assembly and stylet slidably disposed within the needle lumen. The needle retraction mechanism includes a biasing member, actuable locking arrangement and locking mechanism. When the actuable locking arrangement is actuated, the biasing member causes the needle to axially translate over the stylet during retraction to cause delivery of an implant to a target location. The stylet may be retracted following delivery. Methods of assembling, manufacturing, and using are also provided.

Inventors:

Shetty; Gautam N. (Pikesville, MD), Weir; Aaron M. (York Haven, PA), Brandt; Christian P. (York, PA), Castagna; Lou (Middletown, PA), Brenner; Tod H. (Pequea, PA)




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theadder
Posted on: Sep 2 2014, 08:27 PM


Group: Member
Posts: 5,264

hmmmmm
  Forum: By Share Code

theadder
Posted on: Aug 26 2014, 10:22 PM


Group: Member
Posts: 5,264

Hi PeterH,

Haven't been around sharescene for awhile, however, an email alert popped up for EOS so here I am.

How are you going????

Also a nice mention here a couple of hours ago from The World Today...

http://www.abc.net.au/news/2014-08-26/elec...eal-wit/5697544

Good Luck to all holders... biggrin.gif

I do not hold EOS..


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theadder
Posted on: Dec 3 2012, 08:19 PM


Group: Member
Posts: 5,264

When you see this side....then we will be where we belong..

Cowan, Watson, Kawaja, Clarke, Hussey, Warner, Payne, Pattison, Cummins, Starc & Lyon

Pleny of othet good bowlers around like Johnson Cutting Siddle Harris Helfenhaus but batting is thin...
  Forum: Off Topic Chat

theadder
Posted on: Nov 30 2012, 11:13 AM


Group: Member
Posts: 5,264

hi wolv, now we have a good comparison...

Tony Abbott is as good a performer in politics

as Ricky Ponting was in captaining Australia..

Time for both to go, then going forward both teams performance will improve immensely..


This is IMHO... biggrin.gif

Bring on the cricket stuff the politics... devilsmiley.gif
  Forum: Off Topic Chat

theadder
Posted on: Nov 26 2012, 10:50 AM


Group: Member
Posts: 5,264

come on now wolv...fess up... devilsmiley.gif

Yes he did screw Katich, no doubt about it it. The public took to him and I think he received
a very valuable lesson about the Aussie ethics and learnt from it.
He went from a "Hollywood sportsman" who the public detested, without doubt.

He now comes over as a genuine Aussie sportsman in peak batting form and leading
a average cricket team very successfully...

I had my doubts about about him, however, one has to admit he seems to be the man.. cool.gif

Where is Jaytee when I need support???
  Forum: Off Topic Chat

theadder
Posted on: Nov 25 2012, 10:20 PM


Group: Member
Posts: 5,264

Indication is Patterson joins Cummins and is out for the rest of the season...

Should see Starc in action now, surely????
  Forum: Off Topic Chat

theadder
Posted on: Nov 25 2012, 03:02 PM


Group: Member
Posts: 5,264

Hi frodo, I think you need to take into account Patterson will not bowl in this innings therefore
Clarke needs time to get the South Africans out.

It is very hot in Adelaide today and tomorrow so testing times in particular for fast bowlers.
He has allowed time for them to rest and come back strong in short spells.

When they are both resting the only front line bowler left is Lyons so there will be many overs bowled by
part time bowlers. In these periods not many wickets would be expected.

South Africa need a record last wicket score to win the match.

Clarke needs time to do it and he has allowed the time for his bowlers to achieve it.

If by some sort of miracle South Africa make the runs...I would be the first to say well done.
  Forum: Off Topic Chat

theadder
Posted on: Nov 22 2012, 06:33 PM


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Posts: 5,264

Great double ton by Clarke, and centuries to Hussey and Warner.

Fantastic EOD score with full credit to the above however, special mention

to Warner who set the tempo early to initiate the onslaught.

Great day for Michael Clarke and for Australian Cricket...bring on tomorrow...


Sad to see Starc miss out again IMHO opinion a future star..

Look forward to the day when we see Paterson, Cummins and Starc as the fast bowling team...
  Forum: Off Topic Chat

theadder
Posted on: Nov 7 2012, 12:21 PM


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Posts: 5,264

Metal Storm looks to lock and load new debt restructure

http://www.couriermail.com.au/business/met...4-1226511776060
Attached thumbnail(s)
Attached Image


 
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theadder
Posted on: Oct 24 2012, 06:01 PM


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Posts: 5,264

Looking into Callums' figures further..prior to this season for South Australia..

65 matches

121 innings

35.33 Average

7 centuries & 25 half centuries...

Now Adelaide Oval

32 matches

59 Innings

Average 33.96

Only 1 ton in 59 innings on Adelaide Oval...the batmens paradise..
  Forum: Off Topic Chat

theadder
Posted on: Oct 24 2012, 05:46 PM


Group: Member
Posts: 5,264

As a staunch South Aussie who loves his cricket:

Callum Ferguson looks to have all the goods but what a disappointment he has been.

Averages in the 30s with half his games played on Adelaide Oval, the best batting wicket in the world.

No consistancy in his batting, lovely technique but keeps getting out...

Can not see him playing many tests for Australia...hope I'm wrong.. wink.gif
  Forum: Off Topic Chat

theadder
Posted on: Oct 24 2012, 04:51 PM


Group: Member
Posts: 5,264

Siddle couldn't bowl me....bring on Cummins, Pattison & Starc

Then watch the South Africans jump around....but the old school tie boys will be in the 1st

Test...nothing surer..
  Forum: Off Topic Chat

theadder
Posted on: Oct 12 2012, 09:38 AM


Group: Member
Posts: 5,264

Casey Analyst Forecasts Explosive Biotech Growth

http://jutiagroup.com/20121011-casey-analy...biotech-growth/


It’ll start with a trickle, more than a flood. But make no mistake: RNAi, or
temporary gene silencing through interference with the messenger RNA that signal
cell behavior, looks to be one of the most important genetic treatment
methodologies yet conceived.
Genetics are at the root of just about every major chronic disease—heart disease, cancer, diabetes. Gene silencing has serious promise with regard to controlling the root causes and predispositions for some of these maladies, instead of waging continuous battles against symptoms, as we do today.

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theadder
Posted on: Jul 29 2012, 04:52 PM


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Posts: 5,264

RIP Arvet

All the best Blue
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theadder
Posted on: Jul 21 2012, 02:00 PM


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Posts: 5,264

One would think Metal Storm would need to find a "White Knight" ready

to finance the company in the next couple of days...
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theadder
Posted on: Jul 11 2012, 05:12 PM


Group: Member
Posts: 5,264

from ADM defence..

EOS and Hyundai join forces for remote weapon systems

http://www.defencesuppliers.net.au/news/eo...-weapon-systems
Attached image(s)
Attached Image

 
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theadder
Posted on: Jul 6 2012, 10:27 AM


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Posts: 5,264

hi olebluetwo'

Haven't been to the other site for a few days so have been and had a look.

Just the usual change of attitude on a week by week basis, depending on
the post heading

Commercialization = TRL9 preceded by lower TRLs as you go through the process.

No technology is able to by pass the system.

Some posters seem to think Metal Storm can get contracts with technology that is

not mature..

No mention even of TRL 7 for Metal Storm so still years down the track, if they can survive..
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theadder
Posted on: Jun 30 2012, 11:21 AM


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Posts: 5,264

Mission Payload Module update

The purpose of this modification is to extend the proposal due date as identified in the SUMMARY OF CHANGES

SECTION A - SOLICITATION/CONTRACT FORM
The required response date/time has changed from 10-Jul-2012 03:30 PM to 24-Jul-2012 03:30 PM.

https://www.fbo.gov/?s=opportunity&mode...re&_cview=1
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theadder
Posted on: Jun 21 2012, 10:18 AM


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Posts: 5,264

Spar Over Gene-Silencing Patent Is a Federal Case


http://www.courthousenews.com/2012/06/20/47637.htm


CHICAGO (CN) - Adispute over patent rights to a much-anticipated method of gene silencingshould not head to state court merely because one of co-owners to the patent isa state school, a federal judge ruled.

The University ofUtah sued four private research institutes and officials with the University ofMassachusetts over patent rights to ribonucleic acid interference (RNAi), alsoknown as gene silencing.

RNAi switches offa gene by preventing certain RNA molecules from producing proteins in the cell."It has great potential therapeutic value," U.S. District Judge PattiSaris explained.

The University ofUtah's lawsuit seeks to name one of its faculty members, Dr. Brenda Bass, aseither the sole inventor or joint inventor of two RNAi-related patents, knownas Tuschl II patents for the first named investor, Dr. Thomas Tuschl.

"The claimsof the Tuschl II patents are directed to methods of preparing a particular typeof double-stranded RNA molecule that can mediate RNAi," Saris wrote."The molecule has a '3' overhang,' a sequence of nucleotides on one end ofan RNA strand that hangs over the other RNA strand and make up adouble-stranded RNA molecule."

Though the UMassofficials claimed that they have sovereign immunity as state actors, Sarisapplied an exception to that rule because, "unlike disputes over lakes,rivers, and state boundaries, a quarrel over patent rights does not implicatecore sovereign interests."

The University ofUtah dropped Massachusetts as a party to the federal complaint to precludeexclusive jurisdiction in the state Supreme Court, and there is no supportbehind claims that the state is "an indispensible party," thedecision states.

"A judgmentrendered in UMass' absence will not prejudice UMass or the other parties,"Saris wrote. "UMass' interests are well represented by the otherdefendants, internationally renowned research institutions and a university, aswell as the state officials themselves.

Another dismissalattempt against the inventorship claims - this time from all of the defendants,including the Massachusetts Institute of Technology and Alnylam Pharmaceuticals- argued failure to state a claim.

But Saris said"there are allegations of interaction between Dr. Bass and the namedinventors."

The secondamended complaint "alleges that Dr. Bass published an article explainingthe capability to mediate RNAi in mammals with dsRNA fragments having a 3'overhang," she wrote. "The named inventors read her article, andincorporated her work. She also discussed her conception with the namedinventors at two conferences and over dinner.

Federal Circuitcaselaw is clear that there is 'no bright-line standard' in determining jointinventorship," the decision concludes.



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theadder
Posted on: Jun 20 2012, 10:03 AM


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http://www.lifescientist.com.au/article/42...file_bionomics/
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theadder
Posted on: Jun 20 2012, 10:00 AM


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Posts: 5,264


Benitec Biopharma moves towards human clinical studies for HIV/AIDS and Hepatitis C
Wednesday, June 20, 2012 by Christine Feary
http://www.proactiveinvestors.com.au/compa...nitec+Biopharmahttp://www.proactiveinvestors.com.au/compa...is-c-30331.html

Benitec Biopharma
(ASX: BLT) is progressing towards human clinical studies with the company’s multiple gene silencing technology programs.

Trials of Benitec’s HIV/AIDS program have showed that the ddRNAi construct still expresses 3.5 years after the patient’s stem cells were transfected with a lentivirus construct.

Benitec licensee Calimmune is targeting a clinical trial in HIV/AIDS patients in 2012, the first trial to use only ddRNAi constructs to target HIV in patients.

In the United States, Benitec subsidiary Tacere Therapeutics has progressed the company’s Hepatitis C program to the point where an Investigational New Drug application is being prepared.

Discussions with the US Food and Drug Administration are advanced.

Already a large amount of clinical trial data has been manufactured, with a U.S. based clinical trial to begin as early as 2013.

Meanwhile, pre-clinical testing of lead compounds for use in treating cancer-associated pain has been simplified, with all test species confirming strong activity against the target gene.

Production of a material suitable for pre-clinical and clinical trials is now underway.

Testing of Benitec’s other programs, which target areas such as non-small cell lung cancer, hepatitis B and oculopharyngeal muscular dystrophy, are also progressing well.

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theadder
Posted on: Jun 14 2012, 02:43 PM


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Posts: 5,264

Page 4... Benitec gets a mention

New! dd-RNAi compound Gene silencing Benitec, Australia, Biomics, China Benitec.com Preclinical


http://www.hepb.org/pdf/2012%20Spring_B%20Informed_Final.pdf
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theadder
Posted on: Jun 13 2012, 02:28 PM


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Posts: 5,264

MLGLS Presentation at the recent Joint Armaments Conference
Attached File(s)
Attached File  Tuesday14135orrison.pdf ( 231.87K ) Number of downloads: 173

 
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theadder
Posted on: Jun 13 2012, 12:44 PM


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Posts: 5,264

EOS announce new $25 million contract

http://www.defencesuppliers.net.au/news/eo...llion-contract1
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theadder
Posted on: Jun 5 2012, 12:41 PM


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Posts: 5,264

Plastic...you have been asked to get your facts right...I assume you refer to me here:

"But I have no intention of pandering to a couple of johnny-come-latelies"

I wouldn't usually bother with this type of comment but I do not want my credibility
questioned by you or anyone in fact I have been here and posting at BLT site since Feb 18th 2004.

There are 628 BLT pages my posts commence on 627 yours when ?????

Lo and behold I can not find a post by you prior to this....but there could be.

So if I am a Johny-come-lately where are you placed in the line... now know to me as Johnny Plastic..
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theadder
Posted on: Jun 4 2012, 02:40 PM


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Posts: 5,264

come on plastic, it is not hard to supply links to your information

Links shows the credibility of your posts.

Not only in relation to posts but to the individual also.


So put up or ??????
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theadder
Posted on: Jun 3 2012, 01:51 PM


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Posts: 5,264

olebluetwo.... reason being same old same...
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theadder
Posted on: May 31 2012, 07:36 PM


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In the FILE WRAPPER I found this under the heading of CLAIMS for the mentioned latest published application
Attached File(s)
Attached File  13290609.pdf ( 143.82K ) Number of downloads: 628

 
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theadder
Posted on: May 31 2012, 07:10 PM


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Posts: 5,264

Family of theGraham patent 6,573,099

title ~ SYNTHETIC GENES AND GENETIC CONSTRUCTS COMPRISINGSAME I

Granted Patents

10/346,853 filed on 01-17-2003

10/821,726 filed on 04-08-2004

11/218,999 filed on 09-02-2005

10/646,070 filed on 08-22-2003

10/759,841 filed on 01-15-2004


Abandoned applications

09/646,807 filed on 12-05-2000

09/997,905 filed on 11-30-2001

10/821,710 filed on 04-08-2004

11/180,928 filed on 07-13-2005


Reissue/Reexamination applications


90/007,247 filed on 10-04-2004

90/008,096 filed on 05-18-2006



Pending patent application (Not published so contents can not be viewed)

13/290,609 filed on 11-07-2011 which is Pending

This application was filed on 7
th of November2011 a late application (after re-exam

documents filed) so one would assume something of importance in here..(In relation to science)

This application has been published on the USPTO site today so the contents can be seen.

Maybe those up with the science may be able to see the importance in this late addition.

http://appft.uspto.gov/netacgi/nph-Parser?...0531+AND+ICN/au)

United States Patent Application 20120135517

Kind Code A1

Graham; Michael Wayne ; et al. May 31, 2012


SYNTHETIC GENES AND GENETIC CONSTRUCTS

Abstract

The present invention relates generally to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of atransgenic organism, in particular a transgenic animal or plant. Moreparticularly, the present invention provides novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto.


Inventors: Graham; Michael Wayne; (Jindalee, AU) ; Rice; Robert Norman; (Sinnamon Park, AU)

Assignee: Commonwealth Scientific and Industrial Research Organisation

Serial No.: 290609

Series Code: 13

Filed: November 7,2011

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theadder
Posted on: May 29 2012, 06:50 PM


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Posts: 5,264

hi swarth, I have asked at the other site anyone who is attending to ask these questions:

1. Technology Maturity (TRLs)

2. Do they have Patent Insurance???

3 The term of the patents....time remaining..

In my opinion these are the main problems for anyone interested in the long term viability of Metal Storm.


Timeframe and finances we are already aware of these problems
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theadder
Posted on: May 29 2012, 11:07 AM


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Posts: 5,264

Intra-lesional administrations of TG1042 (adenovirus expressing interferon-γ) combined with adoptive TIL transfer in patients with metastatic melanoma.


http://abstract.asco.org/AbstView_114_94729.html
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theadder
Posted on: May 24 2012, 04:54 PM


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Posts: 5,264

At the JOINT ARMAMENTS CONFERENCE, EXHIBITION & FIRING DEMONSTRATION from MAY 14-17, 2012

WWW.NDIA.ORG/MEETINGS/2610

"21st Century Weapon Systems - Providing the Right Response"

George Orrison, MetalStorm, Inc. Had a presentation at


NDIA TUESDAY MAY 15 2012 -

CONCURRENT SESSIONS 14135 - Multi-Grenade Launcher System (MGLS)

http://www.ndia.org/meetings/2610/Document...enda_Onsite.pdf


http://proceedings.ndia.org/2610/14135.pdf
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theadder
Posted on: May 24 2012, 10:10 AM


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Posts: 5,264

Bright ideas go unrewarded:

http://afr.com/p/sections/features/bright_...BA5lYiBVAHw2KAJ
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theadder
Posted on: May 23 2012, 04:16 PM


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Posts: 5,264

yep tban.. fiscal year 2013 begins on October 1, 2012 and ends on September 30, 2013.

http://www.senate.gov/reference/glossary_t...fiscal_year.htm
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theadder
Posted on: May 23 2012, 12:27 PM


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Posts: 5,264

All documentation with todays additions..

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theadder
Posted on: May 23 2012, 12:23 PM


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Posts: 5,264

Update to Mission Payload Module Documentation on the FBO site

Firstly the MASTER PLAN showing contract award as Q1 FY13

M6785412R1014Attachment_6_Integrated_Master_Plan.pdf
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theadder
Posted on: May 21 2012, 12:08 PM


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Posts: 5,264

This is how southern people say and sometimes write Mississippi; Mississippi-iss=Missippi
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theadder
Posted on: May 21 2012, 10:55 AM


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Posts: 5,264

Pain Program Benitec Validated by independent study

http://transitionsanddiabetes.org/pain-pro...ependent-study/
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theadder
Posted on: May 11 2012, 01:58 PM


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Posts: 5,264

welcome bb33 ... biggrin.gif
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theadder
Posted on: May 3 2012, 10:07 PM


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Posts: 5,264

From the USPTO yesterday another patent grant.


http://patft.uspto.gov/netacgi/nph-Parser?...0501+AND+ACN/au)
United States Patent 8,167,837

Judd , et al.

May 1, 2012

Controlled retraction syringe and plunger therefor

Abstract

A retractable syringe (11) and plunger (20) therefore areprovided, whereby the plunger comprises a controlling means (62) whichfacilitates control of the rate of retraction of the retractable needle. Bycontrolling the rate of needle retraction, the likelihood of blood spatteringis reduced, thereby improving the user-friendliness and appeal of theretractable syringe. Typically, the syringe is a prefilled syringe. Followingplunger depression, a symmetrical ejector member (92) releases the retractableneedle (40) from a retaining member (30) to thereby allow retraction of theretractable needle. Needle retraction is facilitated by a biasing means (70),such as a spring or other compressible and/or de-compressible device. Theplunger comprises a plunger housing (21), in which is located the controllingmeans. The controlling means may be a pneumatic air space (324) inside theplunger housing which automatically acts against the retracting needle tothereby control or regulate the rate of retraction.

Inventors:

Judd; Damien (Heathmont, AU

Kaal; Joseph Hermes(Morpeth, AU)

Thorley; CraigStephen (Largs, AU)

Assignee: UnitractSyringe Pty Ltd. (Sydney, New South Wales, AU)

Appl. No.: 11/911,481

[size="3"][/size]
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theadder
Posted on: May 3 2012, 10:01 PM


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Posts: 5,264

Another member of the Graham '099 patent family reached patent status at the USPTO yesterday

http://patft.uspto.gov/netacgi/nph-Parser?...0501+AND+ACN/au)
United States Patent 8,168,774

Graham , et al.

May 1, 2012

Control of gene expression

Abstract

The present invention relates generally to a method ofmodifying gene expression and to synthetic genes for modifying endo geneexpression in a cell, tissue or organ of a transgenic organism, in particular atransgenic animal or plant. More particularly, the invention utilizesrecombinant DNA technology to post-transcriptionally modify or modulate theexpression of a target gene in tissue, organ or whole organism, therebyproducing novel phenotypes. Novel synthetic genes and genetic constructs whichare cap repressing delaying or otherwise reducing the expression of anendogenous gene or a target gene in an organism when introduced are alsoprovided.

Inventors: Graham;Michael Wayne (Chapel Hill, AU), Rice; Robert Norman (Sinnamon Park, AU)

Assignee: Commonwealth Scientific and Industrial ResearchOrganisation (Campbell, AU)

Appl. No.: 11/218,999

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theadder
Posted on: Apr 24 2012, 02:07 PM


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Posts: 5,264

give it to them wolv...JT will be proud of you.. devilsmiley.gif
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theadder
Posted on: Apr 18 2012, 04:35 PM


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Posts: 5,264

Metal Storm receives $4.6m backing from European investor, nears non-lethal weapon production

http://www.proactiveinvestors.com.au/compa...tion-27785.html
Attached image(s)
Attached Image

 
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theadder
Posted on: Apr 17 2012, 10:27 PM


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Posts: 5,264

from the USPTO today..

http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&u=%2Fnetahtml%2FPTO%2Fsearch-adv.htm&r=27&f=G&l=50&d=PTXT&p=1&p=1&S1=(20120417.PD.+AND+au.INCO.)&OS=isd/04/17/2012+and+icn/au&RS=(ISD/20120417+AND+ICN/au)

United States Patent 8,156,868

O'Dwyer

April 17, 2012

Projectile for use in a barrel with a plurality of stackedprojectiles

Abstract

A projectile for use in a barrel with stacked projectiles,particularly for a weapon which can be reloaded by a user in the field. Theprojectile includes a chamber containing a propellant charge, with an exit fromthe chamber for release of propulsion gases into the barrel. A seal blocks theexit and is opened by ignition of the propellant within the chamber but isresistant to gases produced by ignition of propellant in other projectiles inthe barrel. The exit and seal are provided in a range of different forms. Theexit may be an aperture in a wall of the chamber with the seal as a moveablebarrier, such as a valve-like structure, for example. The seal may also includea rupturable or deformable barrier across the aperture. Alternatively the sealis a thin barrier around the charge such as a wax coating and the exit involvesa disintegrable character of the barrier. The seal may also be an inherentproperty of the geometry of the chamber.

Inventors: O'Dwyer; Sean Patrick (Coorparoo, AU)

Assignee: Metal Storm Limited (Richlands, Queensland, AU)
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theadder
Posted on: Apr 6 2012, 11:53 AM


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Posts: 5,264

http://itbriefing.net/modules.php?op=modlo...15&catid=40
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theadder
Posted on: Mar 14 2012, 06:05 PM


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Posts: 5,264

the prompt reply is appreciated... thumbdown.gif
  Forum: Off Topic Chat

theadder
Posted on: Mar 8 2012, 09:33 AM


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Posts: 5,264

just for clarification of the dates regarding the contract for the MPM-NLW I am taking
direct from the other site a post by Tell (Thanks Tell)

Request for Proposal during 2nd Qtr FY12..is now in the progess...

With the contract to be awarded in 3rd Qtr FY12


The U.S. government's fiscal year begins on October 1 of the previous calendar year and ends on September 30 of the year with which it is numbered. Prior to 1976, the fiscal year began on July 1 and ended on June 30. The Congressional Budget and Impoundment Control Act of 1974 stipulated the change to allow Congress more time to arrive at a budget each year, and provided for what is known as the "transitional quarter" from July 1, 1976 to September 30, 1976. As stated above, the tax year for a business is governed by the fiscal year it chooses.[17]

For example, the United States government fiscal year for 2012 ("FY 2012" or "FY12") is as follows:

1st Quarter: October 1, 2011 - December 31, 2011
2nd Quarter: January 1, 2012 - March 31, 2012
3rd Quarter: April 1, 2012 - June 30, 2012
4th Quarter: July 1, 2012 - September 30, 2012
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theadder
Posted on: Mar 7 2012, 08:20 PM


Group: Member
Posts: 5,264

On the other site there has been mention that the MPM contract/award is in April 2012

Just to clarify this from the solicitation it is clear the:

http://en.wikipedia.org/wiki/Request_for_proposal

Request for Proposal during 2nd Qtr FY12

Marine Corps Systems Command (MARCORSYSCOM) intends to issue a full and open competitive solicitation (Request for Proposal) during 2nd Qtr FY12 for the Engineering and Manufacturing Development (EMD) of a Mission Payload Module - Non-Lethal Weapon Systems (MPM-NLWS).

then:

MARCORSYSCOM intends to award one (1) Cost-Plus Fixed-Fee (CPFF) contract for the EMD Phase only in 3rd Qtr FY12 with a period of performance of 36 months

Now here is the full Pre-solicitation where the info came from..

Solicitation Number: M67854-12-R-1014

Notice Type: Pre-solicitation

Synopsis:

PRE-SOLICITATION NOTICE: This is a Pre-solicitation Notice; no proposals are being requested at this time. A draft Request for Proposal (RFP) is attached to this pre-solicitation notice for industry comment. Marine Corps Systems Command (MARCORSYSCOM) intends to issue a full and open competitive solicitation (Request for Proposal) during 2nd Qtr FY12 for the Engineering and Manufacturing Development (EMD) of a Mission Payload Module - Non-Lethal Weapon Systems (MPM-NLWS). This system, comprised of a new launcher and a new round of non-lethal ammunition, is to provide the Marine Corps with improved counter-personnel, non-lethal capabilities. The system will dispense a new non-lethal munitions that will suppress personnel through light, sound, and pressure stimuli and will provide longer range, greater area coverage, extended duration, and better scalability of effects than current non-lethal weapon systems. It is to be mounted onto the Marine Corps Transparent Armor Gun Shield (MCTAGS), as well as employed in a dismounted/ standalone ground-based configuration. The EMD Phase Statement of Work (SOW) will include requirements for systems engineering, design, integration, test, manufacture, and delivery of the MPM-NLWS launcher and munitions for Government Developmental Test (DT), as well as configuration management and support to the Program Manager, Non-Lethal Systems (PM NLS). The effort shall be focused on the precise delivery of non-lethal effects against area targets with an enhanced pyrotechnic (thermobaric) payload. It is anticipated that initial delivery of the MPM-NLWS for DT will be required within 20-months after contract award.

The Marines Corps procurement objective for this effort is currently estimated at 312 launchers. The Draft Request for Proposals, SOW, CDRLS, and Government Test Operating Procedures are posted in conjunction with this notice. A copy of the Draft Performance Specification will be provided to interested parties that submit a request to bernetta.burton@usmc.mil provided that they have a valid CCR registration and are not on the Excluded Parties Listing. All request should include the point of contact, company name, cage code and duns number. Interested parties should thoroughly read and review the attached documents to further gain an understanding of the proposed requirement.
The Government is seeking questions and comments on the Draft RFP to be considered and possibly incorporated into the Final RFP. All comments and questions shall be submitted on or before 21 February 2012 by 3:30 PM (EST). Interested offerors shall submit their comments, questions, and recommendations to Ms. Bernetta Burton, Contract Specialist, at email: bernetta.burton@usmc.mil and copy Ms. Patsy Stefan, Contracting Officer, at patsy.d.stefan@usmc.mil.

MARCORSYSCOM intends to award one (1) Cost-Plus Fixed-Fee (CPFF) contract for the EMD Phase only in 3rd Qtr FY12 with a period of performance of 36 months. Award will be made to the responsible offeror whose proposal represents the best value to the Government considering technical, management, and cost factors, and associated sub-factors. The contract will contain options for Low-Rate Initial Production (LRIP) and Full-Rate Production (FRP) allowing the Government to decide to either execute the contract options following the EMD Phase completion or to re-compete for LRIP/FRP based on a Government Business Case Analysis to be conducted prior to Milestone C. The applicable NAICS code for this requirement is 332995 and 332992. The Government will issue the Final RFP and any amendments thereto through the Government-wide point of entry, Federal Business Opportunities (FEDBIZOPPS), via electronic posting through http://neco.navy.mil. Paper solicitations will not be issued. It is the offeror’s responsibility to monitor the internet and obtain the solicitation documents and any amendments.

To be eligible for contract award, offerors shall be registered in the Online Representations and Certifications Application (ORCA) site found at https://www.bpn.gov/. Interested offerors shall also be registered in the Central Contractor Registration (CCR) site found at http://www.bpn/gov/ccr and registration shall also identify the applicable NAICS code: 332995 and 332992. This requirement will be solicited on an unrestricted basis. This is a pre-solicitation notice. No responses to this pre-solicitation notice are required to be eligible to bid on the Final RFP. No additional information will be provided prior to the release of the solicitation. NO PHONE CALLS WILL BE ACCEPTED. ALL COMMUNICATION SHALL BE MADE VIA THE CONTRACTING OFFICE. PROSPECTIVE OFFERORS ARE CAUTIONED AGAINST UNAUTHORIZED COMMUNICATION WITH THE SOURCE SELECTION TEAM. The solicitation will identify instructions to offerors for proposal submission and the protocol for submitting questions for this requirement.
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theadder
Posted on: Mar 7 2012, 07:35 PM


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Posts: 5,264

Hello there ADMIN the questions has been asked recently (poster nebo) however, without a response.

So I will ask this time on entering the sharescene site I am getting

"Do you want to keep running scripts on this page"

no other sites, just here, so one would assume you have a problem????
  Forum: Off Topic Chat

theadder
Posted on: Mar 7 2012, 01:25 PM


Group: Member
Posts: 5,264

From the USPTO yesterday....more IP for Metal Storm... laugh.gif

http://patft.uspto.gov/netacgi/nph-Parser?...2012+and+acn/au
United States Patent 8,127,685

O'Dwyer , etal.

March 6, 2012

Modification of a projectile for stacking in a barrel

Abstract

An existing projectile (21) is modified by adding a tailpiece (22) to enable axial stacking of multiple projectiles (20) in a commonbarrel. Propellant for each modified projectile (20) is contained in respectivechambers located external to the barrel and connected to the bore of the barrelthrough associated ports. Tail piece (22) aligns with a respective port and providesa space between consecutive projectiles (20) into which the propellant gasexpands after ignition. Separate claims are directed to tail assembly (22),modified projectile (20), the barrel assembly having a plurality of projectiles(20) stacked in end-to-end relation, and to an external initiation system forthe barrel assembly (see FIGS. 4, 7).

Inventors: O'Dwyer;James Michael (Brisbane, AU), O'Dwyer;Sean Patrick (Brisbane, AU)

Assignee: Metal Storm Limited (Queensland, AU)

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theadder
Posted on: Mar 7 2012, 01:16 PM


Group: Member
Posts: 5,264

A granted patent from the USPTO yesterday..

http://patft.uspto.gov/netacgi/nph-Parser?...0306+AND+ACN/au)

United States Patent 8,129,510

Kay , et al.

March 6, 2012

Minigene expression cassette

Abstract

Methods and compositions for expressing a gene or nucleotidesequence of interest are provided. The compositions include an expressioncassette that includes a synthetic enhancer, a transthyretin promoter, and anucleotide sequence operably under the control of the synthetic enhancer andthe transthyretin promoter. The expression cassette may be used in anadeno-associated viral (AAV) vector, such as a self-complementary AAV vector.

Inventors: Kay; Mark(Los Altos, CA), Hebert; Micheal(Sunnyvale, CA), Roelvink; PetrusWilhelmus (Gaithersburg, MD), Suhy;David A. (San Ramon, CA)

Assignee: The Board of Trustees of the Leland StanfordJunior University (Palo Alto, CA)

Benitec Biopharma Limited (Balmain, NSW, AU)

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theadder
Posted on: Mar 7 2012, 11:30 AM


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Posts: 5,264

apparently not... biggrin.gif
  Forum: Off Topic Chat

theadder
Posted on: Mar 6 2012, 07:44 PM


Group: Member
Posts: 5,264

http://www.defencesuppliers.net.au/home/de...efence-week-194
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theadder
Posted on: Mar 1 2012, 02:56 PM


Group: Member
Posts: 5,264

olebluetwo, tban has given the answer

"Hope for a miracle"

Metal Storm IMHO must win the Mission Payload Module contract or it is all over..

Should they win this contract the payment will not give them the finances they need going forward.

However it will give them the credibility required to get investers interested again..
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theadder
Posted on: Mar 1 2012, 02:22 PM


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Posts: 5,264

expectation...that is all that has kept us here for how long????

seems like 100 years... laugh.gif
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theadder
Posted on: Feb 16 2012, 10:41 AM


Group: Member
Posts: 5,264

Firm Focuses Operations on Gene Silencing

http://www.genengnews.com/gen-articles/fir...silencing/4004/
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theadder
Posted on: Feb 14 2012, 07:55 PM


Group: Member
Posts: 5,264

Hi Henrietta gone very quiet here..

From the USPTO today a granted patent:

http://patft.uspto.gov/netacgi/nph-Parser?...0214+AND+ACN/au)
[/size]United States Patent 8,114,050

Kaal , et al.

February 14,2012

________________________________________

Controlled retraction syringe and plunger therefor

Abstract

A retractable syringe (10) and plunger (20) therefore areprovided, the syringe having a barrel (20), a retractable needle mount (40) towhich is mounted or is mountable a needle (11), and a plunger (80), the plungercomprising an initially compressed spring (60), a means for engaging theretractable needle mount, an integrally formed plunger seal (22) and aremovable controlling means (70) for facilitating control of the rate ofretraction of needle mount when engaged with plunger. The needle mount is heldin the barrel by a holding means which prevents inadvertent retraction of theneedle mount when the plunger is withdrawn to fill the syringe. The holdingmeans comprises a plurality of clips (196A, 196B, 196C) that may be integrallyformed with the barrel or may be present on a cap mounted to the barrel. Anejector means (52) is also provided, whereby plunger depression can urge theejector means to release the needle from the holding means and thereby allowretraction of the needle mount following decompression of the spring.

________________________________________

Inventors: Kaal;Joseph Hermes (Morpeth, AU), Thorley; CraigStephen (Largs, AU), Judd; Damien (Coomera Springs, AU)

Assignee: UnitractSyringe Pty Ltd (Sydney, New SouthWales, AU)

Appl. No.: 11/914,092

[size="3"]
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theadder
Posted on: Feb 14 2012, 06:27 PM


Group: Member
Posts: 5,264

well if this happens to everyone when they try to log into the email you sent there is a problem

The error returned was:
You are not allowed to use the messenger feature on this board

been using it since day one check my membership number

Tried it four times for the same result..


  Forum: Off Topic Chat

theadder
Posted on: Feb 8 2012, 11:43 AM


Group: Member
Posts: 5,264

Metal Storm needs to win the recent solicitation (Non Lethal MPM) to show the market the technology is required as well as the short term requirement for credibility.

Now I want to point you to:
http://www.metalstorm.com/

at the bottom of the page:
Australia Land Warfare Conference 2010 ...page 12 on the brochure Mission Payload Module (MPM) take a good look at the 15 barrel set up..now this was 2010.

Moving forward to the present at the Department of Defense Non-Lethal Weapons Program site..

http://jnlwp.defense.gov/developing/MPM_NLWS.html

Now this is the department that is issueing the solicitation for this program going forward..

http://jnlwp.defense.gov/solicitations/default.html

Do you see what I see or am I being too optimistic
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theadder
Posted on: Feb 7 2012, 10:25 PM


Group: Member
Posts: 5,264

a patent from the USPTO today..

http://patft.uspto.gov/netacgi/nph-Parser?...0207+AND+ACN/au)

United States Patent 8,109,212


O'Dwyer

February 7, 2012

Sleeved projectiles

Abstract

A projectile (10) is for use with barrel assemblies of thetype having a plurality of projectiles axially disposed within a barrel havinga bore and a muzzle and which projectiles are associated with discretepropellant charges for propelling said projectiles sequentially through themuzzle of the barrel. Projectile (10) comprises expandable sleeve (11) encirclingat least part of core (12). Sleeve (11) and core (12) have wedging surfaces(14) operable to deform trailing part (21) of sleeve (11) into sealingengagement with the bore in response to pressure exerted on the projectile(10). When projectiles (10) are axially disposed in the bore, rear face (24) ofthe leading projectile cooperates with leading face (20) of the trailingprojectile to define a discrete space about spine (23) for receipt of thepropellant charge. Sleeve (11) is retained about the core (12) during travel tothe target.

Inventors: O'Dwyer; James Michael (Brisbane, AU)

Assignee: Metal Storm Limited (Brisbane, AU)

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theadder
Posted on: Feb 7 2012, 08:39 PM


Group: Member
Posts: 5,264

hi techtrad

I also have grey hair and balding nearing 67 years of age

so I suppose on stats I have more time available to wait for an out come... laugh.gif

But like Metal Storm no guarentees available there either...lol

We hang in by a thread.... IMHO we have to win the Non lethal MPM solicitation

or it's all over... weirdsmiley.gif
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theadder
Posted on: Feb 7 2012, 04:06 PM


Group: Member
Posts: 5,264

http://hotcopper.com.au
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theadder
Posted on: Feb 4 2012, 10:06 PM


Group: Member
Posts: 5,264

Non Lethal 2012 report....from JNLWP site...good reading to see direction of the program..

Mission Payload Module gets a mention on pages 10 & 22...

http://jnlwp.defense.gov/pdf/annualreport/...nualreport.html
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theadder
Posted on: Feb 3 2012, 11:16 AM


Group: Member
Posts: 5,264

If you can access this site there is more detailed requirements re this solicitation.

https://www.neco.navy.mil/biz_ops/necoattach.aspx?soln13=M6785412R1014


I can see at the FBO site Combined Systems have put their name forward in the interested parties...

https://www.fbo.gov/index?s=opportunity&...mp;tabmode=list
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theadder
Posted on: Feb 2 2012, 09:50 AM


Group: Member
Posts: 5,264

hi tban this is the one we need to win...hang in there... laugh.gif

https://www.fbo.gov/?s=opportunity&mode...re&_cview=0

Feb 01, 2012
A--Presolicitation Notice (Draft Soliciation) Mission Payload Module-Non-Lethal Weapons Systems (MPM-NLWS)

Solicitation Number: M6785412R1014

Agency: Department of the Navy
Office: United States Marine Corps
Location: Marine Corps Systems Command

Solicitation Number: M6785412R1014
Notice Type:Presolicitation

Synopsis:

Added: Feb 01, 2012 4:25 pm
Marine Corps Systems Command (MARCORSYSCOM) is releasing a Draft Request for Proposal (DRFP) M67854-12-R-1014 for the anticipated procurement of a Mission Payload Modules- Non-Lethal Weapons Systems (MPM-NLWS). This is a draft solicitation only. It is not the intention of the Government to enter into a contract based on this notice or to otherwise pay for information that is submitted. If the Government decides to contract for this effort, it will issue a Final Request For Proposal on or about 10 April 2012.

This will be a full and open competitive acquisition for procurement of the Engineering and Manufacturing Development (EMD) of a Mission Payload Module - Non-Lethal Weapon Systems (MPM-NLWS).

This system, comprised of a new launcher and a new round of non-lethal ammunition, is to provide the Marine Corps with improved counter-personnel, non-lethal capabilities. The system will dispense a new non-lethal munitions that will suppress personnel through light, sound, and pressure stimuli and will provide longer range, greater area coverage, extended duration, and better scalability of effects than current non-lethal weapon systems. It is to be mounted onto the Marine Corps Transparent Armor Gun Shield (MCTAGS), as well as employed in a dismounted/ standalone ground-based configuration. The EMD Phase Statement of Work (SOW) will include requirements for systems engineering, design, integration, test, manufacture, and delivery of the MPM-NLWS launcher and munitions for Government Developmental Test (DT), as well as configuration management and support to the Program Manager, Non-Lethal Systems (PM NLS).

The effort shall be focused on the precise delivery of non-lethal effects against area targets with an enhanced pyrotechnic (thermobaric) payload. It is anticipated that initial delivery of the MPM-NLWS for DT will be required within 20-months after contract award.

The Marines Corps procurement objective for this effort is currently estimated at 312 launchers. The applicable NAICS code for this requirement is 332995 and 332992. The Draft Request for Proposals, SOW, CDRLS, and Government Test Operating Procedures are posted in conjunction with this notice. A copy of the Draft Performance Specification will be provided to interested parties that submit a request to bernetta.burton@usmc.mil provided that they have a valid CCR registration and are not on the Excluded Parties Listing.

All requests should include the point of contact, company name, cage code and duns number. Interested parties should thoroughly read and review the attached documents to further gain an understanding of the proposed requirement.

The Government is seeking questions and comments on the Draft RFP to be considered and possibly incorporated into the Final RFP. Initial questions and comments shall be submitted no later than 3:30 PM, EST Tuesday, 21 February 2012, in writing to bernetta.burton@usmc.mil and copy to patsy.d.stefan@usmc.mil. The Government will address all questions and comments received up to this date and time. The Government’s response will be issued on the Federal Business Opportunities website via the Navy Electronic Commerce Online entry point.

No telephone calls will be answered or returned.

Contracting Office Address:

M67854 MARINE CORPS SYSTEMS COMMAND 2200 Lester Street Quantico, VA

Point of Contact(s):

Bernetta Burton (703)432-XXXX

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theadder
Posted on: Jan 17 2012, 08:41 AM


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Posts: 5,264

SciGen eyes Middle East and Africa markets for sale of recombinant human insulin

http://www.proactiveinvestors.com.au/compa...lin--24199.html
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theadder
Posted on: Jan 12 2012, 10:20 AM


Group: Member
Posts: 5,264

Metal Storm in halt ahead of shareholder meeting
12 Jan 2012

Metal Storm Ltd has been placed in a trading halt, ahead of separate meetings with its shareholders
and noteholders as it seeks approval for an amendment to the terms of its convertible notes.

The weapons manufacturer will remain in a halt until an announcement from the company
or the beginning or normal trading on January 16.

The meetings will seek shareholder approval for an amendment to the terms of convertible notes offered
by the group.

If approved, the maturity date of the notes will be extended by three years
from March 1 2012 to March 1 2015.

The conversion price formula will also be changed so that it favours noteholders.

Shares in Metal Storm last traded at 0.2 of a cent.
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theadder
Posted on: Dec 28 2011, 04:06 PM


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Posts: 5,264

Hussey and Ponting put us back in the game...

In comes Haddin with a chance to show some disciplined batting
and stay in with Hussey who was batting well.

Oh no.. two undisciplined wooshes and a poke at a wide ball outside
off stump...why do the selectors keep picking him..
  Forum: Off Topic Chat

theadder
Posted on: Dec 28 2011, 11:32 AM


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Posts: 5,264

Non-Lethal Weapons (NLW)Reference Book 2011

http://info.publicintelligence.net/DoD-NLW.pdf
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theadder
Posted on: Dec 25 2011, 12:27 PM


Group: Member
Posts: 5,264

Where's Katich good question however to me the selectors are hard understand.

Mitchell Johnson left arm fast bowler has had huge problems bringing the ball back
into the righthand batsmen but has still been able to hold his place in the side
by slanting the ball accross the right handers.

Now guess what we find a big tall left armer called Starc who brings the ball back viciously
to the right handers with lift and good control(Taking into account his age and experience)

Where is he...no bring back Hilfenhaus...
All I can say is Patterson had better turn it on again.

Selectors indicated they needed Hilfenhaus as a stock bowler..well that was what they said Siddell
was in the side for.

Now we have Patterson and two stock bowlers all right handers thus no variety...

Let's have a look at the batting now. how could they drop Kawaja who has been pushed into
first wicket down and in my opinion has done as well as could be expected.

The two wickets we played New Zealand on were moving/seaming wickets..all batsmen found it hard
to make runs.

The more placid wickets are to be used now where you can hit through the line of the ball with confidence.
No opportunity for Kawaja and Hughes to capitalise eject them and let Ponting and Hussey cement their places
again

These are the wickets the new boys should be playing on to get confidence at this level...

That's enough.. gives me the shits...

Give the kids ago.. the mob we keep using have been letting us down for years.
  Forum: Off Topic Chat

theadder
Posted on: Dec 25 2011, 11:36 AM


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Posts: 5,264

from the North American Technology Demonstation 2011 pics..may be of interest
Attached thumbnail(s)
Attached Image


 
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theadder
Posted on: Dec 25 2011, 11:03 AM


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Posts: 5,264

Yep begins on January the 23d and the animal sign is the Dragon..

the date plastic mentioned was for 2011 and was the rabbit..... lmaosmiley.gif
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theadder
Posted on: Dec 21 2011, 10:22 PM


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Posts: 5,264

http://www.msnbc.msn.com/id/45740538/ns/te...nce-innovation/
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theadder
Posted on: Dec 21 2011, 10:40 AM


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Posts: 5,264

Stunning — that's the kind of weapon US Special Ops wants

Military envisions non-lethal canister fired by grenade launcher to stop vehicles

http://www.msnbc.msn.com/id/45740538/ns/te...innovation/
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theadder
Posted on: Dec 21 2011, 10:31 AM


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Posts: 5,264

http://www.genomeweb.com/rnai/dicerna-aims...rship-12-ind-13
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theadder
Posted on: Dec 9 2011, 11:22 AM


Group: Member
Posts: 5,264

EOS revamps US operations for next CROWS bid

http://www.australiandefence.com.au/news/e...-next-crows-bid
Attached image(s)
Attached Image

 
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theadder
Posted on: Dec 5 2011, 01:01 PM


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http://www.slideshare.net/BenitecLtd
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theadder
Posted on: Dec 5 2011, 10:46 AM


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Posts: 5,264

UK's FDS Pharma acquires SciGen Israel for $2m

http://www.globes.co.il/serveen/globes/doc...00703312


More then a penny perhaps... rolleyes.gif
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theadder
Posted on: Dec 2 2011, 10:34 PM


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rough end of the pineapple I reckon...lol... lmaosmiley.gif
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theadder
Posted on: Dec 2 2011, 08:05 PM


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yes wolv, one of those catches that a good first slipper would swallow, however, it
is not a position he usually fields. Watson is normally there.

It takes a natural to be a good first slipper.

It was one of those catches - awkward height - where you can be caught out
fingers up or fingers down.

If you look closely you can see the hands are at the maximum height for the fingers
down position.

This is where you would see Ponting bending the knees dropping the body and catching
with the fingers pointing upwards..in front of the eyes..

Captain is a very good fielder without a doubt, but not a first slipper...
  Forum: Off Topic Chat

theadder
Posted on: Nov 30 2011, 09:41 PM


Group: Member
Posts: 5,264

a Granted patent from the USPTO last night..one of the Graham '099 family

http://patft.uspto.gov/netacgi/nph-Parser?...1129+AND+ICN/au)

United States Patent: 8,067,383

Graham , et al.

November 29, 2011

Synthetic genes and genetic constructs comprising same I

Abstract

The present invention relates generally to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention provides novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto.

Inventors: Graham; Michael Wayne (Jindalee, AU), Rice; Robert Norman ( Sinnamon Park, AU)

Assignee: Commonwealth Scientific and Industrial Research Organisation (Campbell, AU)

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theadder
Posted on: Nov 30 2011, 09:13 PM


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Posts: 5,264

has this been seen before..

http://www.benitec.com/documents/vanleeuwe...nitecreport.pdf
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theadder
Posted on: Nov 27 2011, 10:45 AM


Group: Member
Posts: 5,264

Hi Chiller,

The gamest selector of all time...you have flicked our "Hollywood" captain.
  Forum: Off Topic Chat

theadder
Posted on: Nov 26 2011, 01:42 PM


Group: Member
Posts: 5,264

I agree bam_bamm Katich should be in the side, however, his altercation
with the now captain puts him in the never ever basket..

Taking into account he now is one of the selectors..

Katich is a tough, gritty, top batsman who gives his all. Not the
flashy "Hollywood" players we seem to have in abundance.

IMO we should have a separate test team to the other forms of the game.

I once read a top football coach said "Footballers are bricks with ears"

The same seem to apply to most sportsmen it seems once you get them out of
their comfort zone they seem to struggle.

Changing from the "Undisciplined Shots" of one day cricket seems to be a struggle
for our batsmen.

Enough from me... biggrin.gif
  Forum: Off Topic Chat

theadder
Posted on: Nov 25 2011, 06:57 PM


Group: Member
Posts: 5,264

Hi Henrietta,

Except for Siddle I don't mind your side either, except Watson has written he
finds it hard to open the batting when he has bowled.

So to me there is a need to put him down the order as we need his bowling
desperately..

He has been magnificent opening the batting however we do need his all round
ability..

This is the main reason I have kept Johnson I see he gives you much more
then Siddle...Although it is very clear Siddle gives it all.

Ponting has been and still is a great batsman/team member, I just thought it
was the time for the changing of the guard when we played New Zealand.

We can see with Marsh, Kawaja and Cummins that change was needed and
has been good...
  Forum: Off Topic Chat

theadder
Posted on: Nov 25 2011, 05:02 PM


Group: Member
Posts: 5,264

Hi Henrietta,

If I was selecting the side and all palyers being available this would be my 12

in batting order:

Marsh, Hughes,Kawaja,Watson,Clark,Hussey,Payne,Johnson,Harris, Cummins, Cutting & Lyon.

Hughes will get there give him time. Kawaja is the man. Watson at 4 so he can bowl more.

Payne a good gloveman who puts value on his wicket and can bat.. Johnson stays as he is still
a match winner...his batting was a large part in us winning the last test. Like the look of Cutting.
Lyon not really a class spinner but the best around..

Now your turn..
  Forum: Off Topic Chat

theadder
Posted on: Nov 25 2011, 04:51 PM


Group: Member
Posts: 5,264

mentioned in the ADM..(Australian Defence Magazine)

http://www.australiandefence.com.au/news/a...e-to-trial-maul
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theadder
Posted on: Nov 22 2011, 09:59 PM


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Posts: 5,264

Mention in the ADM...

Aussie police to trial MAUL

http://www.australiandefence.com.au/news/a...e-to-trial-maul
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theadder
Posted on: Nov 17 2011, 11:16 AM


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Posts: 5,264

Alnylam Pharmaceuticals Grants InterfeRxâ„¢ Intellectual Property License to Sylentis for Development and Commercialization of RNAi Therapeutics


CAMBRIDGE, Mass. & MADRID, Nov 16, 2011 (BUSINESS WIRE) -- Alnylam Pharmaceuticals, a leading RNAi therapeutics company, and Sylentis, S.A., a Spanish bio-pharmaceutical company devoted to the research and development of new therapies based on RNAi, announced today that Alnylam has granted Sylentis a non-exclusive option for a new target-specific InterfeRxâ„¢ license. This license would enable the discovery, development, and commercialization of a synthetic siRNA directed towards an undisclosed target for the treatment of glaucoma. Sylentis' program is currently in a Phase I/II clinical trial. Upon Sylentis' exercise of this option, Alnylam would receive upfront and milestone payments, as well as royalties on sales of products covered by the licensing agreement. Additional financial details were not disclosed. Sylentis is a wholly owned subsidiary of Grupo Zeltia (mc:ZEL). "We are pleased to be granting Sylentis a new InterfeRx license, thereby enabling their efforts with access to Alnylam intellectual property which we believe is critical for the development and commercialization of RNAi therapeutics," said Laurence Reid, Ph.D., Senior Vice President and Chief Business Officer of Alnylam. "The agreement with Sylentis represents continued progress with our InterfeRx program, an important part of our overall strategy to create value today by leveraging our intellectual property portfolio."

"Sylentis is focused on designing, developing, and commercializing RNAi therapeutics to treat serious medical conditions such as glaucoma. This license from Alnylam is an important step for us to further advance our glaucoma program in human clinical studies," said Jose Maria Fernandez Sousa, President of Grupo Zeltia.

Alnylam created the InterfeRx licensing program to grant licenses under its intellectual property to biotechnology and pharmaceutical companies wishing to pursue RNAi therapeutics against specific targets outside Alnylam's core strategic interests. To date, a total of six companies are InterfeRx licensees; the license grants cover fourteen active target programs including four in clinical development. In addition to Sylentis, Alnylam's InterfeRx licensees include Calando Pharmaceuticals, Inc., Tekmira Pharmaceuticals Corporation, Quark Pharmaceuticals, Inc., GeneCare Research Institute Co., Ltd., and, under an option agreement, Benitec Ltd.
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theadder
Posted on: Nov 10 2011, 12:52 PM


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from SpaceWar...

http://www.spacewar.com/reports/Australian...m_MAUL_999.html
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theadder
Posted on: Nov 9 2011, 02:14 PM


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hi henrietta...from the USPTO yesterday a granted patent..

http://patft.uspto.gov/netacgi/nph-Parser?...1108+AND+ACN/au)

United States Patent 8,052,654

Kaal , et al.

November 8, 2011

Automatically disabled syringe

Abstract

A syringe (10) has a plunger (20), a barrel (11) and acollar (40, 50) with two pawls (42A, 42B). The plunger has two opposed ratchets(23A, 23B) that align with the one each of the pawls and thereby or impede,withdrawal of the plunger during or following depression of the plunger. Thebarrel has a collar with an inner (50) and an outer member (40) that areincapable of rotation relative with respect to each other. The outer member hasthe two pawls (42A, 42B) and two fingers that slidably engage opposed guideslots (28) on the plunger to thereby prevent or minimize rotation of theplunger relative to the collar. The inner member of the collar is operable toprevent engagement of the plunger ratchet by the two pawls until the plunger isdepressed.

Inventors: Kaal;Joseph Hermes (Morpeth, AU), Thorley; Craig Stephen (Largs, AU), Judd; Damien(Heathmont, AU)

Assignee: UnitractSyringe Pty Ltd. (West Perth, Western Australia, AU)
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theadder
Posted on: Nov 8 2011, 03:17 PM


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yep tban...the TRL level is mentioned Oh No!!!!....TRL 6

I was hoping the TRL levels were not as stringent with the Non lethal

Seems TRLs are similar numbers as lethal???? indicating a long track ahead still.

Finance and timeframe still a huge hurdle...

Now what's that...

"Fortune favours the brave"

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theadder
Posted on: Nov 8 2011, 09:30 AM


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Australian Police to Trial Metal Storm MAULâ„¢

Brisbane, Australia – 8 November 2011: Metal Storm Limited.

Metal Storm is pleased to announce that two Australian Police Forces have formally requested an

opportunity to trial the Metal Storm MAULâ„¢ 12-gauge weapon system.

BREON Defence, the Asia Pacific TASER distributor and Metal Storm's exclusive distributor for law

enforcement in Australia & New Zealand, has delivered the formal requests on police letterhead to the

Company.

Metal Storm CEO, Dr Lee Finniear said that MAULâ„¢ was creating a great deal of enquiry and

requests for trials from around the world, however as an Australian Company getting the interest of the

Australian Police is a very important step forward.

"Internationally MAULâ„¢ continues to gather momentum even before we enter production", he said. "At

present we have formal enquiries and/or requests for trial from 46 US domestic law enforcement

agencies, 6 US Federal law enforcement agencies and 11 other international law enforcement

agencies." he said. "However, as Australians we attach great importance to assisting our own police

forces to obtain the benefit of our developments".

Director of BREON Defence, Mr George Hateley said he could see a very clear future for MAULâ„¢ in

Police operations.

"As a Director of BREON and a former member of the Victoria Police Special Operations Group (Anti-

Terrorist Unit) I have a great deal of experience knowing what Tactical Special Operations and law

enforcement officers need in their respective roles in 'High Risk' entries under warrant, and in the

arrests of potential violent and or armed offenders," he said.

"When I saw MAULâ„¢ I recognised it as an incredibly flexible non-lethal/lethal weapon when compared

to what is currently available. We are 100% confident in our initial enquiries with specialist law

enforcement units around Australia that the weapon will easily fit into the holistic weapons package

and minimise what needs to be carried in the future in 'High Risk' tasks".

The Company recently announced it is collaborating with TASER International to integrate TASER

capabilities into MAULâ„¢ using the TASER XREP projectile and increase its capability for law

enforcement operations.

The Company is currently undertaking a Rights Issue to raise capital. Part of the raising will be used

to progress MAULâ„¢ toward full production to satisfy the growing demand for the weapon.

Dr Finniear said, "Recent published market research states that the global non-lethal weapons market

is expected to grow three-fold by 2020. Demand for MAULâ„¢ is undeniable and getting this weapon

into production is a top priority for the Company" he said. "In the short term we are focusing our

resources onto MAULâ„¢ to meet this growing demand for trials and the potential for near term

deployments."

MAULâ„¢ is a small, lightweight, semi-automatic launcher that has been designed for both law

enforcement and military use. It can be used with non-lethal, door breaching or lethal projectiles and

can be configured with a shoulder stock, as a pistol or as an under-barrel attachment to another

weapon. Its diminutive size and weight make it ideal for urban situations where officers have to

operate in confined spaces, and need a weapon that can fulfil a variety of mission critical functions.

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theadder
Posted on: Nov 7 2011, 06:48 PM


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http://www.nps.edu/Academics/Schools/GSOIS...nts/Events.html
F. Irregular Warfare (IW)
1. All Optical Tunnel and IED Detection System - US Seismic Systems INC.,
2. Automatically Detecting Suicide Bombers at Standoff Distances - SET Corp.
3. IED Locator/Imager with a Built-in Navigator – Geophex, USASOC
4. Integrated Force Protection Light - AeroVironment, ATK, L3, USSOCOM
5. Managed Lethality Grenade Launcher system (MLGLS) - Australian Defence Science Technology Organisation (DSTO), Metal Storm Limited, Airtronic USA
6. Small UAS Taggant Delivery and Communications Node - Lockheed Martin, USASOC
7. Thermal Matrix ACT (Access Counter IED) Concealed Object Threat Detection Test - Thermal Matrix
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Posted on: Nov 7 2011, 06:23 PM


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USSOCOM-NPS Field Experimentation Cooperative

Tactical Network Testbed (TNT) 12-1

Experiment # F-05

Managed Lethality Grenade Launcher system (MLGLS) Of Delivering Kinetic Energy to a Human Target Over a Larger Target Range


Attached File(s)
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theadder
Posted on: Nov 4 2011, 11:44 AM


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Non-Lethal Weapons (NLW) Reference Book June 2011


we find mention of -Multi-Shot Accessory Underbarrel Launcher (MAUL).-in the document under the heading of:

NLW Vendor Listing

The compilation of commercial products below does not constitute an endorsement or solicitation by the Joint Non-Lethal Weapons Directorate.

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theadder
Posted on: Nov 4 2011, 11:29 AM


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Latest... Mission Payload Module – Non-Lethal Weapons System (MPM-NLWS) fact sheet

http://jnlwp.defense.gov/pdf/pressroom/MPM...%20Oct%2011.pdf


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theadder
Posted on: Nov 1 2011, 03:29 PM


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Non lethals helping on the home front

another nice video

http://centralny.ynn.com/content/top_stori...the-home-front/
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theadder
Posted on: Oct 31 2011, 03:38 PM


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Battlefield Gadgets

another nice video

http://centralny.ynn.com/content/top_stori...efield-gadgets/
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theadder
Posted on: Oct 30 2011, 10:48 AM


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Non-lethal force demand growing around the globe...

***watch the video

http://centralny.ynn.com/content/top_stori...ound-the-globe/
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theadder
Posted on: Oct 28 2011, 12:33 PM


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NON-LETHAL CAPABILITIES ON EXHIBITION AT 2011 NATD

Background

In 2004, the Conference of National Armaments Directors(CNAD) established the Defence Against Terrorism Program of Work (DAT POW) in response to the new security challenges posed by terrorism and all asymmetricthreats.

Initially, 10 POW were put in place. Later on, the NATOoperational community underlined its need for better and more flexible responsecapabilities to minimize collateral damage, as current capability deficienciesare creating Escalation of Force situations which endanger both civilians andmilitary forces alike, causing needless injury, failure of mission, andpolitical fallout. In response, the fall 2007 CNAD agreed to create an 11th DATPOW area on Non -Lethal Capabilities, with Canada volunteering to lead thisnewest DAT POW initiative.

DAT 11 has been working with the Counter -TerrorismTechnology Unit (CTTU) to form the WG with a view to deliver non lethaltechnologies to ISAF within three years.

The WG is open to NATO nations, and Non NATOCountries, including Partners for Peace (PfP) nations, approved by CNAD. DAT 11coordinates with Topical Group 3, also Non Lethal Capabilities (NLC), but witha wider mandate and timeline within the NATO Army Armaments Group (NAAG).

DAT 11 Mandate

To confirm and demonstrate existing, or soon to be fielded(Technical Readiness Levels 7 to 9), non lethal technologies with a view to facilitating the rapid fielding of non lethal capabilities in support of theNATO mission in Afghanistan (ISAF) and in Counter Terrorism operations.

Criteria

To support the DAT 11, some 35 non lethal tasks wereselected from amongst 104 NATO defined non lethal tasks. On 16 Feb 2010, ACT endorsed five SAS 078 nonlethal weapons requirement categories including crowd control incapacitate individuals or groups, deny an area topersonnel, deny an area to vehicles, vessels and aircraft, and disable or neutralizevehicles, vessels, aircraft and equipment.

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theadder
Posted on: Oct 28 2011, 12:17 PM


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2011 North American Technology Demonstration

http://ottawa.openfile.ca/blog/curator-blo...pons-technology

Metal Storm are part of the dynamic demonstration which is very encouraging, however, the part that I like most is this:

NON-LETHAL CAPABILITIES ON EXHIBITION AT 2011 NATD

To confirm and demonstrate existing, or soon to be fielded (Technical Readiness Levels 7 to 9), non-lethal technologies with a view to facilitating the rapid fielding of non-lethal capabilities in support of the NATO mission in Afghanistan

So one would assume from this Metal Storm has Non Lethal weapons at TRL 7 to 9 levels...nice to know..
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theadder
Posted on: Oct 27 2011, 08:59 PM


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a "pending patent application" published at the USPTO today..

http://appft1.uspto.gov/netacgi/nph-Parser...1027+AND+ICN/au)


United States Patent Application 20110263508


Kleinig; Michael John ; et al.

October 27, 2011

Compositions and methods for including melanogenesis in asubject

Abstract

Described herein are compositions comprising an alpha-MSHanalogue and a transdermal delivery system and methods for inducingmelanogenesis and/or preventing UV radiation-induced skin damage in a subjectby topical administration of these compositions.

Inventors: Kleinig; Michael John; (Brunswick, AU) ; Kirby;Kenneth B.; (Palm Beach Gardens, FL) ; Pettersson, JR.; Berno I.; (Perry,GA)

Assignee: Clinuvel Pharmaceuticals Limited


Melbourne

AU

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theadder
Posted on: Oct 24 2011, 06:04 PM


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HopgoodGanim works on $13m acquisition

http://www.thenewlawyer.com.au/article/Hop...ion/532272.aspx

24 October 2011 | by The New Lawyer .

LAW firm HopgoodGanim has advised New York-based investment fund manager Lind Partners on the $13 million acquisition of existing secured convertible notes in ASX-listed Metal Storm Limited, and the establishment of a separate equity line of $900,000 with Metal Storm.

According to partner Michael Hansel, who led the team at HopgoodGanim on the deal, raising capital through flexible equity funding arrangements is becoming an increasingly popular option for Australian companies.

“HopgoodGanim has advised on a number of equity line transactions in recent times. These types of arrangements offer a real opportunity for companies who would otherwise be unable to secure capital or debt funding from more traditional sources, such as banks or institutional placements.”

He said Lind Partners invests across a broad range of industries and economic environments, and is one of many US-based companies looking to secure equity in Australian companies.

“Americans are certainly looking to increase their exposure in Australian markets, possibly to diversify their investments and spread their risk.

“This appetite for Australian investment is something that companies across the country can take advantage of in order to raise capital for expansion programs or to reduce debt.”
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theadder
Posted on: Oct 22 2011, 01:21 PM


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New vaccine promises to arrest spread of lung cancer

http://timesofindia.indiatimes.com/india/N...ow/10446720.cms

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theadder
Posted on: Oct 16 2011, 09:34 AM


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Unilife is mentioned in the latest ISIPS report

http://www.isips.org/reports/ISIPS_Newslet...er_14_2011.html

http://www.marketwatch.com/story/unilife-w...ance-2011-10-05
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theadder
Posted on: Oct 3 2011, 10:35 AM


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Non-Lethal Weapons: Technologies & Global Market – 2012-2020

http://www.homelandsecurityresearch.com/20...arket-2012-2020

Cost $4,450.00

At a quick glance there is particular mention of Metal Storm in the document..

1.7..........
Mission Payload Module

28.2.17...MAUL (Multi-shot Accessory Under-barrel Launcher)

28.2.18....Firestorm Grenade Launcher

29.26......Metal Storm Limited









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theadder
Posted on: Sep 28 2011, 09:51 PM


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cool.gif ..yep...better get back on my medication..
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theadder
Posted on: Sep 28 2011, 01:19 PM


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Benitec Limited (ASX:BLT) Announce A Board and Senior Management Update


MAR 29, 2010 10:54 - Article Views: 3,314
Benitec Limited (ASX:BLT) (PINK:BNIKF) announced today that Ms Sue MacLeman will step down from the role of Chief Executive Officer (CEO) and Managing Director to pursue other opportunities. She has agreed however to stay actively involved with Benitec as a Strategic Advisor at this exciting time for the Company. A transition arrangement has been put in place. Mr Mel Bridges and Dr John Chiplin will both move to Executive Director roles within the Company and the Board will be further strengthened in the coming months.
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theadder
Posted on: Sep 21 2011, 11:21 PM


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From the USPTO a granted patent on 20th Sept 2011

http://patft1.uspto.gov/netacgi/nph-Parser...0920+AND+ACN/au)

United States Patent 8,021,333

Kaal , et al.

September 20, 2011

Syringe spring retainer

Abstract

A spring retainer (60) for a syringe (10) that has a barrel(40), a plunger (20), a spring (90) and a retractable needle (50) that cancouple with the plunger for spring-driven retraction of the coupled needle andplunger. The spring retainer has first (70) and second (80) body members thatcooperate to releasably maintain the spring in a compressed state until theplunger is coupled to the retractable needle after depression of the plunger todeliver the fluid contents of the syringe. Depression of the plunger triggersrotational disengagement of the first and second body members to allowdecompression of the spring which forces retraction of the needle into thebarrel. Rotational disengagement of the first and second body members alsoassists rotation of the plunger into a final, inoperable position.


Inventors: Kaal;Joseph Hermes (Morpeth, AU), Thorley; Craig Stephen (Largs, AU)

Assignee: Unitract Syringe Pty Ltd. (Sydney, New South Wales,AU)

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theadder
Posted on: Sep 20 2011, 01:09 PM


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couple of items may be of interest

http://americaninvestmentclub.com/benitec-...ain-specialists

http://www.genomeweb.com/rnai/benitec-star...n-rx-toward-hum
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theadder
Posted on: Sep 17 2011, 06:17 PM


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Couple of documents which mention Metal Storm..

www.dtic.mil/ndia/2011smallarms/Tuesday12145Gandy.pdf

www.dtic.mil/ndia/2011smallarms/WednesdayWeapons12482Harris.pdf

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theadder
Posted on: Sep 16 2011, 12:21 PM


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AUSBIOTECH 2011 CONFERENCE SPEAKERS' PROFILE


Attached File(s)
Attached File  Dr_Peter_French_Bios.pdf ( 307.1K ) Number of downloads: 138

 
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theadder
Posted on: Sep 15 2011, 05:59 PM


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PROBLEM STATEMENT

The U.S. Navy Marine Corps needs a new generation of 40 mm low/medium-velocity

munitions that could provide higher lethality due to airburst capability. This new airburst

munitions have to be compatible with the current legacy systems (M32 Multi-shot and

M203 under barrel launcher) and the anticipated XM320 single shot launcher. The

technology could also be used for non-lethal systems so that a high velocity round could

be slowed at a specific distance from a target.


Attached File(s)
Attached File  PhysOptics3_Brief.pdf ( 470.19K ) Number of downloads: 3436

 
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theadder
Posted on: Sep 15 2011, 01:47 PM


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Yes acreage have been mentioning for years weapon maturity (TRL's)

Until you have numbers you are going nowhere..

However some seem to think the technology is so good it can bypass
the TRL system....

Would they expect any of their loved ones to be in a conflict with a

weapon that has not been certified to be used in the front line....????
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theadder
Posted on: Sep 15 2011, 01:20 PM


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Hi acreage, I did mean to draw to posters attention where this company is upfront with indicating the TRL levels.

Why then do we not see the same for Metal Storm???

This would give us an indication regarding maturity of the technology.
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theadder
Posted on: Sep 15 2011, 12:16 PM


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TECHNOLOGY DEVELOPMENT MILESTONES (SBIR/STTR)


Phase 1

Low Shock acceleration survivability test successfully passed (TRL 4)

4/20/2009

Phase II -

1st year

Moderate Metal Storm was successful in fire test of 40-mm round with SOProF.

0.5 distance range was demonstrated

8/2010

Phase II - 2nd year

Moderate Fire test with 2-m target range 8/2011


Objective:





Currently a contract on delivery of 25 SOProF units for 40-mm airburst round with Metal

Storm is completed. New contract with Metals Storm on delivery of 20 SOProF units for non-lethal

thermobaric 40-mm round started 08/20/2010.

Need additional funding for energy source development and establishing a testing facility.

[size="3"][/size]

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Posted on: Sep 9 2011, 09:01 PM


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http://jnlwp.defense.gov/pdf/pressroom/FY1...ter%20FINAL.pdf

From September 2011 JNLWP Newsletter..

U .S. Marine Corps Systems Command recently held technology demonstrationsfor the developmental Mission Payload Module – Non-Lethal Weapons System.

As part of the system's technology development, projectpersonnel assessed two modified commercial-off-the-shelf, nonlethal, tube-launchedmunitions systems.

They also evaluated whether those systems could meet thenon-lethal weapon counterpersonnel capability requirements for range, accuracyand human effects.

The Mission Payload Module – Non-Lethal Weapons System willpotentially support missions requiring crowd dispersal, area denial, accesscontrol point security, unit defense and convoy security.

"The Mission Payload Module– Non-Lethal Weapons System represents a major Joint project investment by boththe Marine Corps and the Joint Non-lethal Weapons Program.

When fielded to the operating forces, the system willprovide a first-of-its kind, unique counter-personnel capability to combatantcommanders," said Ray Grundy, Branch Head for the Escalation-of-Force Branch,part of Headquarters, Marine Corps Deputy Commandant for Combat Development andIntegration at Marine Corps Base Quantico, Va.

The system includes two components: the launcher system andthe non-lethal munition.

The system's multiple-tube design allows the firing ofseveral non-lethal munitions with greater accuracy and distance than fieldednon-lethal capabilities.

The potential payload is a nonlethal novel pyrotechnicmunition, which has a combined visual and auditory effect.

This past winter, two commercial contractors demonstratedtheir systems to program personnel from Marine Corps Systems Command;

Marine Corps Combat Development and Integration;

Marine Corps Operational Test and Evaluation Activity;

the Joint Non-Lethal Weapons Directorate;

Naval Sea Systems Command; and the Air Force Research Laboratory.

As the lead Service project manager for the Mission PayloadModule – Non-Lethal Weapons System, Marine Corps Systems Command selected thesystems to participate in the demonstration based on program requirements andproposals from the contractors.

Marine Corps Combat Development and Integration, Fires andManeuvers Division, Escalation-of-Force Branch, Non-Lethal Systems is therequirements generator for the Mission Payload Module – Non-Lethal WeaponsSystem project.

The Joint Non-Lethal Weapons Program and the Marine Corpsboth provide funding for the project as the resource sponsors.

The Marine Corps is designing the Mission Payload Module –Non-Lethal Weapons System for infantry units. Marine Corps military policeunits and the other Services have also shown interest in the system.

For the technology demonstrations, developers integrated theMission Payload Module – Non-Lethal Weapons System on a Humvee, but also planto mount the system on other vehicle or ship platforms in future projectincrements.

Thedemonstrations provided data about the Mission Payload Module – Non-Lethal WeaponsSystem that will assist project managers in the technology development process,a step necessary to reach Milestone B, the Technology Development phase of the acquisitionprocess.

"Thetechnology demonstration gives both users and project managers a first-handlook at this exciting capability and its unique functionality during thiscritical phase in the acquisition process," said Ron Smith, Senior RedsearchScientist for Georgia Tech Research Institute at Quantico, Va.

TheAir Force's Human Effects Center of Excellence analyzed the data gathered fromthe Mission Payload Module – Non-Lethal Weapons System technology demonstrationsand, through computer modeling, determined the systems' possible effects on anindividual's sight, hearing and other physiological effects.

MarineCorps Systems Command conducted government testing of the systems' non-lethal munitionat Naval Surface Warfare Center Dahlgren Division. Marine Corps Systems Commandanticipates reaching Milestone B in fiscal year 2012.

[size="3"]

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Posted on: Sep 9 2011, 07:31 PM


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appeared at the JNLWP site..

http://jnlwp.defense.gov/developing/MPM_NLWS.html
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theadder
Posted on: Sep 6 2011, 12:47 PM


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How we can defend manufacturing industry

http://www.theaustralian.com.au/business/o...x-1226130065850

A third example is the breakthrough defence technology developed by Metal Storm. The Queensland company has proved its technology for US military clients but remains zealously ignored by the ADF. As in the solar energy space, Australia Inc has managed to turn its back on a fine Australian invention. I could present many other examples, but space is limited.

Australia's approach to strategic manufacturing for the defence sector is plainly inadequate, indeed perverse. How can Glenn Stevens and the Reserve Bank help solve this problem? The answer is obvious. Keeping interest rates lower than needed to contain inflation will do nothing to help Australian industry, and inflation will damage all industries.
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theadder
Posted on: Aug 30 2011, 11:20 PM


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try this... top right you will find all details, so it is still hanging in there..

http://www.ipo.gov.uk/p-ipsum/Case/Publica...umber/GB2353282
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theadder
Posted on: Aug 30 2011, 11:07 PM


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from the USPTO today a granted patent..

http://patft1.uspto.gov/netacgi/nph-Parser...0830+AND+ACN/au)

United States Patent 8,008,468

Roelvink , et al.

August 30, 2011

RNAi expression constructs with liver-specific enhancer/promoter

Abstract

The present invention provides compositions and methods suitable for RNAi specifically in the liver so as to treat diseases or disorders.

Inventors: Roelvink; Petrus W. (Campbell, CA), Suhy; David A. (Castro, CA), Kolykhalov; Alexander A. (Mountain View, CA), Kay; Mark A. (Los Altos, CA), Giering; Jeffery C. (Burlingame, CA)

Assignee:Benitec, Inc. (Melbourne, AU)
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theadder
Posted on: Aug 29 2011, 03:19 PM


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thumbdown.gif ...last in line...
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theadder
Posted on: Aug 28 2011, 10:19 PM


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hi henrietta if you wish to view the images from the USPTO patent ...

you need to have this softeware Irfanview...download from here:

http://www.uspto.gov/teas/Plugins-IrfanView.html

click on images and all will be revealed once you have irfanview on your PC:

Retractable syringe with plunger disabling system
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theadder
Posted on: Aug 26 2011, 09:39 PM


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market indicates worth is nix..
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theadder
Posted on: Aug 25 2011, 12:18 PM


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this seems to be where we are involved...will venture further later

Section 2.7 (in the pdf)...Non Lethal Systems..
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theadder
Posted on: Aug 24 2011, 10:06 PM


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from the USPTO yesterday a granted patent:

Retractable syringe with plunger disabling system
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theadder
Posted on: Jul 29 2011, 01:10 PM


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I have asked on several occasions if Metal Storm have IP insurance to cover any litigation.

There has never been a reply let alone an answer to this one.

Moosey you seem to have direct contact with Lee, put it to him.

If you think things are bad now...well???

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theadder
Posted on: Jul 27 2011, 04:25 PM


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MoU Limited to Develop TASER Less-Lethal Ammunition for the Metal Storm MAUL Weapon

http://www.correctionsone.com/products/fir...rm-MAUL-Weapon/

Scottsdale, AZ -- TASER International, Inc., a global provider of safety technologies that prevent conflict and protect life, is proud to announce that it has entered into a Memorandum of Understanding (MoU) with Metal Storm Limited and BREON Defence Systems Pty Limited to develop and market TASER® less-lethal ammunition for the Metal Storm MAUL™ weapon.

Under the MoU the parties will collaborate to develop, produce and market Metal Storm MAUL™ ammunition that launches the TASER® Extended Range Electronic Projectile (XREP™).

TASER International manufactures industry leading Electronic Control Devices (ECDs) that are used worldwide by law enforcement, military, correctional services, professional security, and personal protection markets. TASER ECDs use proprietary technology to incapacitate dangerous or high-risk subjects who pose an immediate risk to themselves or others. The use of TASER devices dramatically reduces injury rates for law enforcement officers and suspects.

The TASER XREP is the most technologically advanced projectile ever deployed from a 12-gauge cartridge. It delivers a similar Neuro Muscular Incapacitation bio-effect as handheld TASER ECDs, but can be delivered to a much greater effective range – up to 100 feet from the operator.

Metal Storm’s MAUL is a highly compact, multi-shot 12 gauge launcher that is ideally suited to law enforcement and military applications. It can be fitted as an accessory to an assault rifle, or operated from its own shoulder stock or pistol grip attachments. Weighing just 800 grams, MAUL™ uses Metal Storm’s patented stacked projectile technology to provide semi-automatic fire as fast as the operator can squeeze the trigger. A full weapon reload of up to five rounds takes less than two seconds.

TASER International Chairman and Founder, Tom Smith said that the MAUL and XREP combination would be ideal for sectors of the market where extended range was needed but size and weight had to be minimized. “We developed the XREP to provide an extended range for situations where a close approach was dangerous or not possible,” he said. “MAUL would provide this capability from a very lightweight, compact accessory launcher, rather than the operator having to carry a separate conventional shotgun.”

Metal Storm CEO, Lee Finniear said that the TASER XREP would add a new and highly effective projectile to the MAULâ„¢ less-lethal capability.

“Our objective with MAUL™ has been to deliver a lightweight launcher that complements conventional assault rifles by providing a broad range of capabilities for non-lethal, door breaching and other specialized missions.” he said. “The TASER XREP ammunition will provide the exceptionally versatile TASER Neuro Muscular Incapacitation from the MAUL™ weapon, with the added benefit of a longer range. In our view MAUL™ plus the XREP would be a game changing combination for urban military and law enforcement operations.”

BREON Defence Systems is also a party to the MoU. BREON is the exclusive Asia Pacific Distributor for TASER products, and it recently signed an exclusive distributorship agreement with Metal Storm for MAULâ„¢ for the law enforcement market in Australia and New Zealand. BREON will provide local Australian support for the collaboration, plus assist with the development of effective marketing and business development strategies for the combined system.

About TASER International, Inc.
TASER International, Inc. is a global provider of safety technologies that prevent conflict and protect life. More than 16,200 public safety agencies in 107 countries rely on TASER® electronic control devices (ECDs) and AXON on-officer camera systems to help protect and serve. TASER innovations benefit individuals and families too, providing personal protection and accountability while maintaining regard for life. Since 1994, more than 236,000 individuals have relied on TASER technology as a means for effective personal safety. Learn more about TASER International and its solutions at www.TASER.com and www.Evidence.com or by calling (800) 978-2737. Be a part of the TASER community by joining us on Facebook, Twitter and YouTube.

About Metal Storm
Metal Storm Limited is a multi-national defense technology company engaged in the development of electronically initiated ballistics systems using its unique “stacked projectile” technology. The company is headquartered in Brisbane, Australia and incorporated in Australia. Metal Storm Limited technology and products are represented in the USA by Metal Storm Inc., which has offices in Arlington Virginia.

Metal Storm is working with government agencies and departments, as well as industry, to develop a variety of systems utilizing the Metal Storm non-mechanical, electronically fired stacked ammunition system.

Metal Storm’s weapon technology uses computer-controlled electronic ignition and a system of stacked projectiles, to achieve a completely non-mechanical gun that is very lightweight and compact, providing a very high firepower to weight ratio. The Metal Storm weapons system utilizes multiple barrels mounted together on one platform which allows varying munitions types to be deployed in a single, low cost, lightweight weapon system. Firing the weapons by electronic ignition requires no moving parts, allowing reliable long term unattended weapon operation.



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theadder
Posted on: Jul 27 2011, 01:51 PM


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From the USPTO...

SYNTHETIC GENES AND GENETIC CONSTRUCTS.....US application 10/821,726

has the following in it's file history

07-25-2011 Mail Notice of Allowance
07-21-2011 Notice of Allowance Data Verification Completed
07-21-2011 Document Verification


Good news...Another of the "Pending patent applications" in the graham family has reached Notice of allowance status..

Another Patent in Graham Family Allowed in US

Allowance of Another Key US Graham Family Patent Further

Strengthens Benitec’s ddRNAi Patent Position

27 July 2011, Melbourne, Australia:
Benitec Ltd (ASX:BLT), a world leader in RNA-based gene silencing for human therapeutics, is pleased to report that the United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance on 25 July 2011 for US Patent Application 10/821,726 "Synthetic Genes and Genetic Constructs" (‘726). The allowed claims of ‘726 are complementary to those of the foundational and re-issued ‘099 Graham patent and, as such, provide Benitec with even greater patent protection for use of its DNA-directed RNA interference (ddRNAi) gene silencing technology for human therapeutic applications. The claimed constructs have two sequences which are identical to a "region of a target gene in an animal cell". The "target gene" is not limited in scope.

Dr Peter French, CEO of Benitec said "Benitec has seen several significant patents granted or allowed over the past 12 months in the US, Europe and other jurisdictions. This has greatly turned around Benitec’s position to a point where we once again dominate the gene silencing landscape using ddRNAi. This latest allowance solidly cements that position, and increases the value of Benitec’s patent assets.

"ddRNAi has the potential to permanently silence any genes involved in chronic life threatening disease, and as such is likely to provide the basis for development of a broad range of novel human therapeutics. These patent decisions provide confidence to our existing and potential sub-licensees" he said.

Typically, a granted patent is issued by the USPTO about 4-6 months after a Notice of Allowance.

CSIRO and Benitec are currently awaiting decisions from the USPTO on three other pending applications within the Graham patent family. These applications contain claims that would further strengthen Benitec’s dominant position in ddRNAi.

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theadder
Posted on: Jul 26 2011, 09:13 PM


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from the USPTO today ..a granted patent..

http://patft1.uspto.gov/netacgi/nph-Parser...0726+AND+ACN/au)

United States Patent 7,984,675


O'Dwyer

July 26, 2011

Propellant sealing system for stackable projectiles

Abstract

A projectile for use in a barrel with stacked projectiles, particularly for a weapon which can be reloaded by a user in the field. The projectile includes a chamber containing a propellant charge, with an exit from the chamber for release of propulsion gases into the barrel. A seal blocks the exit and is opened by ignition of the propellant within the chamber but is resistant to gases produced by ignition of propellant in other projectiles in the barrel. The exit and seal are provided in a range of different forms. The exit may be an aperture in a wall of the chamber with the seal as a moveable barrier, such as a valve-like structure, for example. The seal may also include a rupturable or deformable barrier across the aperture. Alternatively the seal is a thin barrier around the charge such as a wax coating and the exit involves a disintegrable character of the barrier. The seal may also be an inherent property of the geometry of the chamber.

Inventors: O'Dwyer; Sean P. (Queensland, AU)

Assignee: Metal Storm Limited (Queensland, AU)



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theadder
Posted on: Jul 25 2011, 09:54 AM


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Metal Storm/TASER develop less-than-lethal ammunition

http://eideard.wordpress.com/2011/07/24/me...hal-ammunition/
Metal Storm and TASER are developing less-than-lethal ammunition for the aptly-named MAUL rapid-fire 12-gauge launcher. The tiny 800 gram MAUL fits on an assault rifle, and shoots five bullets which incapacitate those it hits with the same Neuro Muscular effect of a handheld TASER.

Until very recently, the basic concept of the gun had changed little since the advent of gunpowder, and nearly all guns still run on the same principles. A decade ago, Metal Storm developed a new type of digital gun that is more closely related to the inkjet printer than traditional ordnance.

Its ammunition is stacked, fired electronically and ammunition types can be mixed, enabling the same gun to perform multiple roles.

Meanwhile, the dumb lumps of metal which guns initially fired evolved into intelligent projectiles capable of delivering a range of payloads for everything from door-breaching, grenade launching, and now non-lethal…it says here…

A five round reload takes two seconds and each bullet incapacitates those it hits with the same Neuro Muscular effect of a handheld TASER.

Buck Rogers military geeks are wetting their pants over this one. But, probably not as much as a very few cops who would rather be storm troopers, judge, jury – all rolled into one.

I like the part about the “tiny 800 gram MAUL”. Ever been hit by anything weighing “just” 800 grams fired from a shotgun? It’s gonna make a hole THIS BIG!!



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theadder
Posted on: Jul 23 2011, 07:32 PM


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Long Range Taser Shotgun Is About To Hit The Market

Read more: http://www.businessinsider.com/maul-long-r...7#ixzz1Sv3LhGo8

Australian gun company Metal Storm is doing its best to bring law enforcements desire to incapacitate the general public to greater lengths.

According to Wired, the weapons group is producing a 12-gauge shotgun called the MAUL that will accept several electrically charged cartridges and fire them up to 30 yards away in quick succession.

A reload of all five cartridges apparently takes two seconds.

Taser founders Tom Smith told the guys at Wired his thoughts in development: "We developed the XREP to provide an extended range for situations where a close approach was dangerous or not possible.”

Wired calls it a "remote crowd control of pain."



Read more: http://www.businessinsider.com/maul-long-r...7#ixzz1Sv3VIS3T

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theadder
Posted on: Jul 22 2011, 10:00 AM


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Nice exposure in the Ottawa Citizen..Defense Watch

Australian Firm Says Its Metal Storm Weapons Technology Will Play A Critical Role in Replacement Small Arms for the Canadian Forces
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theadder
Posted on: Jul 22 2011, 09:55 AM


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This is the award Metal Storm is involved with Physical Optics Corporation

http://www.poc.com/

Phase I

Smart Optical Proximity Fuze

Abstract

To address the U.S. Navy Marine Corps need for a new generation of 40 mm low/medium-velocity munitions that could provide higher lethality due to airburst capability, Physical Optics Corporation (POC) proposes to develop a new Smart Optical Proximity Fuze (SOProF) for 40 mm rounds. This proposed SOProF is based on two POC innovations: (1) use for the first time of a new optical fuze design for low-velocity 40 mm rounds, and (2) novel integration of state-of-the-art optical and optimized electronic components. These innovations, utilizing the principle of laser triangulation, will enable the new airburst 40 mm projectile to hit camouflaged and defilade targets without any fuze preset and with minimal modification of the fire control system. SOProF will activate a round payload at the required distance of 2-3 m from the target. In Phase I POC will design and build a prototype SOProF, making maximum use of COTS components, and will demonstrate the feasibility of the SOProF prototype by laboratory and field testing with dummy practice rounds. In Phase II POC plans to optimize the SOProF design for assembly with HE M-406 and M433 40 mm projectiles, and will conduct range testing in cooperation with the customer.

Benefit

Upon successful development, airburst 40 mm low-velocity projectiles assembled with SOProF will increase efficiency and lethality of ground combat operations. Besides military applications, the proposed SOProF, if assembled with nonlethal variable-range kinetic energy projectiles, will greatly enhance the personal safety of American citizens, especially in states where individual use of lethal weapons for self-protection is strongly restricted by legislation. Law enforcement organizations and automobile manufacturers will also benefit from miniature, low-cost optical proximity sensors.

Keywords

Laser triangulation, increasing lethality, airburst, proximity fuze, low-velocity munition


Phase II

Title

Smart Optical Proximity Fuze

Abstract

To address the U.S. Navy Marine Corps need for a new generation of 40 mm low/medium-velocity munitions with higher lethality via airburst capability, Physical Optics Corporation (POC) proposes in Phase II to advance the Phase I Smart Optical Proximity Fuze (SOProF) prototype to an integrated 40 mm munition ready for testing, certification, and productization. SOProF is based on three POC innovations: (1) use of a new axially symmetric optical/mechanical configuration, (2) use of multiple detectors to increase SNR, and (3) novel integration of state-of-the-art optical and optimized electronic components. These innovations, and the principle of laser triangulation, will enable the new 40 mm airburst projectile to hit camouflaged and defilade targets without any fuze preset and with minimal modification to the fire control system. SOProF will activate a round's payload 2-3 m from the target. In Phase II POC will design and build a prototype SOProF, making maximum use of COTS components, integrate it into a 40 mm projectile, and test it in cooperation with Metal Storm Inc. This laboratory and field testing will demonstrate the airburst capabilities of a SOProF prototype assembled with a dummy practice round and an HE airburst round, reaching TRL-5/6 by project end.

Benefit

Upon successful completion at the end of Phase II airburst 40 mm low velocity projectiles assembled with SOProF will increase the effectiveness of ground military operations through higher lethality against concealed or defilade targets and reducing the probability of leaving unexploded ordnance. Besides military applications the proposed SOProF technology can be utilized in collision avoidance systems in ground and aerial vehicles. SOProF sensors, if assembled with nonlethal variable-range kinetic-energy projectiles, will greatly enhance the personal safety of American citizens, especially in states where individual weapon use for self-protection is strongly restricted by legislation.

Keywords

airburst, grenade launcher, proximity fuze, Laser triangulation
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theadder
Posted on: Jul 22 2011, 09:47 AM


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Metal Storm and Taser developing less than-lethal ammunition

http://www.gizmag.com/metal-storm-maul-tas...munition/19284/

http://www.gizmag.com/metal-storm-maul-tas...picture/138250/
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theadder
Posted on: Jul 2 2011, 12:45 PM


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University Science Research Park Celebrates Anniversary

http://www.newswise.com/articles/battle-ag...e-research-park
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theadder
Posted on: Jun 28 2011, 09:17 AM


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Big Pharmas Vying for Product Specific Deals in Global RNAi Industry


http://www.industrytoday.co.uk/pharmaceutical/big-pharmas-vying-for-product-specific-deals-in-global-rnai-industry/5525

With an anticipated change in the patents and licenses scenario in the pharmaceutical industry, it is expected that more firms would explore RNAi technology to offer RNAi based products, says RNCOS.

As per our new research report "Global RNAi Market Analysis", companies working in the RNAi industry are presently interested in a specific RNAi Therapeutics candidate with which they can deal with the external company directly, without the need for an in-house middleman. Our study indicates that, many companies have started looking for this option. For instance, Pfizer has already pursued this alternative pathway as they have partnered the ddRNAi program for HCV with Tacere and a synthetic siRNA candidate from Quark for wet AMD. In both the cases, there seemed to have been little involvement by Pfizer's in-house oligonucleotide therapeutics unit.

Further, recently Marina Biotech announced a product-specific development deal with Swiss drug licensing and development company Debiopharm that covers a pre-clinical stage RNAi Therapeutics program for bladder cancer (via topical LNP-siRNA administration), where much of the early development work will stay with Marina.

Additionally, we have done a thorough and prudent analysis of the global RNAi industry. We have identified that, RNAi is already an established enabling biotechnology product platform and its use in therapeutics and diagnostics may rival products, like recombinant proteins or monoclonal antibodies in future. It is anticipated that, the global RNAi market will grow at a CAGR of around 28% during 2010-2015.

Besides, our study indicates that, presently in the nascent stages, the RNAi industry is gaining ground in the therapeutics arena, with its most promising application being high-throughput screening. The first of the approved RNAi-based drugs are expected to foray into the therapeutics market in 2013.

Further, the US and Europe together account for a lion's share of the global RNAi market. However, research and investments around the globe have spurred the industry performance to a great extent. The governments in various Asian countries, such as Japan, China, India, and Korea have made huge investments for the growth and development of RNAi research in their respective countries.

"Global RNAi Market Analysis" provides thorough research and rational analysis along with reliable statistics of the global RNAi industry. The report provides extensive information and rational analysis of the global RNAi market. It has thoroughly examined market applications, industrial developments, and competitive landscapes to enable clients understand the market structure and its progress in coming years. The report also provides an insight into the different products available in the market on a segment level. Besides, the research contains exhaustive information regarding recent developments in the geographical markets that will help clients in formulating market strategies and assess opportunity areas in the global RNAi market.

About RNCOS:

RNCOS specializes in Industry intelligence and creative solutions for contemporary business segments. Our professionals study and analyze the industry and its various components, with comprehensive study of the changing market behavior. Our accuracy and data precision proves beneficial in terms of pricing and time management that assist the consultants in meeting their objectives in a cost-effective and timely manner

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theadder
Posted on: Jun 26 2011, 08:50 PM


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try here intel01 you should find out what you are after by looking around this site

http://www.google.de/patents/about/7146898...id=3Yp9AAAAEBAJ
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theadder
Posted on: Jun 21 2011, 02:53 PM


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Are you having a good day???
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theadder
Posted on: Jun 21 2011, 11:14 AM


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2nd RNAi Research & Therapeutics Conference

http://www.gtcbio.com/component/conference...arch&cid=32
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theadder
Posted on: Jun 3 2011, 10:51 PM


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Global RNAi Market to Flourish as Extensive Research Floods In
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theadder
Posted on: May 31 2011, 12:05 AM


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from....ASD News

Colt evaluates Metal Storm MAUL for Manufacturing Arrangement

Read more:

http://www.asdnews.com/news/35787/Colt_eva...Arrangement.htm
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theadder
Posted on: May 30 2011, 06:05 PM


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So what is it moosey cloak and dagger again or secrecy act..

This is what t0nes posted (Cut and pasted from his post)

MAUL in use at USMC Training Command 1/10/2010

"Multi-shot Accessory Underbarrel Launcher - in evaluation ..."


From your post I would assume you have see a response from Lee, to him...

You have indicated you are satisfied with the answer...

So we would assume from this, knowing YOU are satisfied his post is 100% correct???
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theadder
Posted on: May 30 2011, 04:53 PM


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I would assume from your post either Lee ignored you or the
reponse he gave you did not substaniate what you posted.

Goodbye & Good Luck
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theadder
Posted on: May 26 2011, 08:38 PM


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well t0nes, as someone suggested in a previous post email the company and ask why it hasn't ben put to the market.

I would be very interested in the response.

You now have the xls sheet send it to them and ask.
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theadder
Posted on: May 26 2011, 12:23 PM


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Navy/Marines Program Elements for FY2012

http://www.dtic.mil/descriptivesum/Y2012_Navy.html

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theadder
Posted on: May 26 2011, 12:08 PM


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well t0nes you have got me moving again...

go to this site and click on BROWSE BY COMPANY and then click on the

"M" you will find Metal Storm and more info there on FIRESTORM as well as MAUL

http://cd.fped8.org/HTML/INITPAGE.HTML
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theadder
Posted on: May 26 2011, 11:58 AM


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Cost Data:
$2,800 - $1,400 for quantity purchase (graduated pricing based on quantities).

pricing of the MAUL??? and nice video..

http://cd.fped8.org/HTML/Products/NLW/14674-NLW-1.htm
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theadder
Posted on: May 26 2011, 11:37 AM


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hi earl, I do hope t0nes is right with his opinion, however, I can not believe
they would not have put it to the market.

It would have to be announced..
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theadder
Posted on: May 25 2011, 08:28 PM


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t0nes I am able to access it without a problem so it must be your security settings..

the keywords xls document is there for you..
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theadder
Posted on: May 25 2011, 08:05 PM


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t0nes..I would be very confident if what you are indicating is correct it would have been announced.

anyhow this is what I could find..you will find the file you refer here..

https://www.trngcmd.usmc.mil/_layouts/OSSSe...rngcmd.usmc.mil


keywords 10.1.10.xls
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theadder
Posted on: May 25 2011, 07:12 PM


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further investigation will give you this:...

M32 Multiple shot Grenade Launcher test model, Marine Air-Ground Task Force (MAGTF) ... 137, Multi-shot Accessory Underbarrel Launcher - in evaluation ...
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theadder
Posted on: May 25 2011, 10:37 AM


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Prima Biomed readies $38m raising ovarian cancer vaccine Cvac.

http://www.theaustralian.com.au/business/o...9-1226062459793
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theadder
Posted on: May 24 2011, 09:54 AM


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Metal Storm ltd waits for contract with PNG

http://www.postcourier.com.pg/20110523/business05.htm
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theadder
Posted on: May 23 2011, 02:02 PM


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Prima Biomed Clinical Trials Offer Significant Upside
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theadder
Posted on: May 23 2011, 01:57 PM


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go here

http://support.microsoft.com/?ln=en-au

put the error you are experiencing in the search and you should find the answer..
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theadder
Posted on: May 22 2011, 01:48 PM


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Cancer collaboration

http://www.virtualmedicalcentre.com/news/c...aboration/16253
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theadder
Posted on: May 20 2011, 10:47 AM


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S&T Activities in Support of the Canadian Small Arms Replacement Program


Attached File(s)
Attached File  12482_1_.pdf ( 62.75K ) Number of downloads: 46

 
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theadder
Posted on: May 20 2011, 10:35 AM


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Metal Storm Rapid Fire Weapons - Why, Carbon Nano-Tube Storm Would Work Better

http://ezinearticles.com/?Metal-Storm-Rapi...&id=6262910
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theadder
Posted on: May 19 2011, 10:02 AM


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from Defence Update..

Metal Storm Introduces a Non-Lethal / Lethal Weapon System Based on Massive Multi-Barrel Version of the FireStorm

http://defense-update.com/wp/20110518_firestorm_fury.html
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theadder
Posted on: May 18 2011, 12:22 AM


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Hi mrbear, yep just hanging in there, needs a large slice of luck from here on in.



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theadder
Posted on: May 17 2011, 04:21 PM


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FY 2010 Accomplishments:

Awarded two technology development (TD) contracts to General Dynamics and Ordnance Tactical Systems and Metal Storm Inc.
The strategy is to use these contractors during the TD Phase to assess the feasibility of suppressing a human target with a thermobaric payload before proceeding into EMD with a single contractor.

The TD Phase will ensure technology is at a Technology Readiness Level - 6 (TRL-6) before proceeding into

note......seems like we are now TRL 6...

EMD.

FY 2011 Plans:

Conduct government tests to evaluate the effectiveness of the non-lethal munitions payloads.
These tests will determine the threshold levels of light, sound, heat, and blast overpressure produced by the contractor's
munitions. The data will be analyzed using government validated and verified (VandV) models developed through the Joint Non-Lethal Weapons Directorate (JNLWD) to determine the level of suppression achieved by munitions.
Additionally, the government will evaluate the technical adequacy of the proposed system design to ensure that technology within the proposed system design can meet performance specifications.
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theadder
Posted on: May 17 2011, 12:13 PM


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What is the TRL of the System please Metal Storm???

No mention again and again..

Until the tchnology reaches TRL 9 it isn't going anywhere...wake up.. rolleyes.gif

TRL please Metal Storm (yep that will be the day)

Still years away I am afraid, however, still holding...miracle required.

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theadder
Posted on: May 11 2011, 07:20 PM


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Exhibit R-2A,

RDT&E Project Justification: PB 2012 Navy

DATE: February 2011

APPROPRIATION/BUDGET ACTIVITY

1319: Research, Development, Test & Evaluation, Navy BA 7: Operational Systems Development

R-1 ITEM NOMENCLATURE

PE 0206623M: MC Ground Cmbt Spt Arms Sys

1901: MC Grnd Wpnry Prod Improvement

B. Accomplishments/Planned Programs

Title: Mission Payload Module (MPM).

Articles:

Description: New weapon system that launches non-lethal payloads to greater ranges with broader area coverage, a greater duration of effects, and volume of fire. This will be initially deployed from the Marine Corps Transparent Armored Gun Shield (MCTAGS) on the High Mobility Multipurpose Wheeled Vehicle (HMMWV'S)

or the HMMWV's replacement vehicle. MPM wil deliver counter-personnel, non-lethal effects applicable to controlling crowds, denying/defending areas,controlling access, and engaging threats.

FY 2010 Accomplishments:

Awarded two technology development (TD) contracts to General Dynamics and Ordnance Tactical Systems and Metal Storm Inc.
The strategy is to use these contractors during the TD Phase to assess the feasibility of suppressing a human target with a thermobaric payload before proceeding into EMD with a single contractor.

The TD Phase will ensure technology is at a Technology Readiness Level - 6 (TRL-6) before proceeding into

note......seems like we are now TRL 6...

EMD.

FY 2011 Plans:

Conduct government tests to evaluate the effectiveness of the non-lethal munitions payloads.
These tests will determine the threshold levels of light, sound, heat, and blast overpressure produced by the contractor's
munitions. The data will be analyzed using government validated and verified (VandV) models developed through the Joint Non-Lethal Weapons Directorate (JNLWD) to determine the level of suppression achieved by munitions.
Additionally, the government will evaluate the technical adequacy of the proposed system design to ensure that technology within the proposed system design can meet performance specifications.

FY 2012 Base Plans:

Continue to conduct government tests to evaluate the effectiveness of the non-lethal munitions payloads.

These tests will determine the threshold levels of light, sound, heat, and blast overpressure produced by thecontractor's munitions. The data will be analyzed using government validated and verified (VandV) models developed through the Joint Non-Lethal Weapons Directorate (JNLWD) to determine the level of suppression achieved by munitions.
Additionally, evaluate the technical adequacy of the proposed system design to ensure
that technology within the proposed system design can meet the performance specifications
Attached File(s)
Attached File  0206623M_7_PB_2012_1_.pdf ( 1.31MB ) Number of downloads: 63

 
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theadder
Posted on: May 10 2011, 08:39 PM


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yes balance.. weirdsmiley.gif
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theadder
Posted on: May 10 2011, 12:08 PM


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METAL STORM COMPLETES MISSION PAYLOAD MODULE CONTRACT




Attached File(s)
Attached File  mst.pdf ( 77.33K ) Number of downloads: 61

 
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theadder
Posted on: May 4 2011, 03:15 PM


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well they haven't done too much right lately...share price tells it all..

What did the market think of the announcement???
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theadder
Posted on: May 3 2011, 06:08 PM


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hi henrietta, from the USPTO today - a granted patent:

http://patft1.uspto.gov/netacgi/nph-Parser...0503+AND+ICN/au)

United States Patent 7,935,087

Judd , et al.
May 3, 2011

Syringe needle sheath

Abstract
A syringe is provided which comprises a barrel (11) and a needle sheath (30) slidably located within the barrel, a plunger (20) with a plunger seal (23), a needle, a needle sheath (30) and a sheath seal (50), arranged so that depression of the plunger forces the needle sheath to move into a position where it covers or at least partly encloses the needle after delivery of fluid contents of the syringe. The needle sheath may be manually actuated or may be actuated by decompression of a spring. The syringe may further comprise a plunger disabling means operable to impede, prevent or otherwise hinder withdrawal of the plunger during or following depression of the plunger. The syringe may be a pre-filled syringe or a syringe which is filled by a user.

Inventors: Judd; Damien (Coomera Springs, AU), Kaal; Joseph Hermes (Morpeth, AU), Thorley; Craig Stephen (Largs, AU)

Assignee: Unitract Syringe Pty. Ltd. (Newcastle, New South Wales, AU)
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theadder
Posted on: Apr 28 2011, 10:35 AM


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Metal Storm [S&P/ASX 200 Industrials]
hits year-low 12th time in one month and 14th time in three months April 27, 2011 15:00:00 AEST

https://www.macquarie.com.au/edge/article/M...00c502890aRCRD/

TRADING FLOOR

Metal Storm (MST.AU), Australia's 66th largest capital goods company by market capitalisation, hit a 52-week low of 0.60c during the day. In the last one month the stock has hit a new 52-week low twelve times and in the last three months fourteen times, pointing to a significant downtrend. The stock price crashed 0.10c (or 14.3%) to close at 0.60c. Compared with the All Ordinaries index, which fell 34.0 points (or 0.7%) on the day, this was a relative price change of -14.3%.



Volatility: the stock traded between an intraday high of 0.70c and a two-day low of 0.60c, suggesting a trading opportunity between peaks and troughs. Today its volatility of 16.7% was 11.3 times its average volatility of 1.5%. A price fall on high volatility is a bearish signal. The average daily volatility of 8.3% places the stock in the 1st quartile in the market meaning it is highly volatile.

Volume: there were 5,820,000 shares worth $39,440 traded. The volume was 1.3 times average trading of 4,430,611 shares.

Volume weighted price (VWP): the price is at a discount of 13.6% to the 1-month volume weighted average price of 1.0c, which may appeal as a value proposition.

Falls to Rises: In the last three months the number of falls outnumbered rises 11:7 or 1.57:1.

Standard Deviation (SD): SD is a statistical measure of deviation from the mean. The SD of 8.5% gives it a percentile rank of 92 meaning that 92% of stocks in the Australian market are less volatile than this stock.

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theadder
Posted on: Apr 27 2011, 09:52 PM


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Arrowhead Research Announces RNAi Leader John J. Rossi, Ph.D. to Join Calando Scientific Advisory Board

http://www.businesswire.com/news/home/2011...i-Leader-John-J.
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theadder
Posted on: Apr 27 2011, 12:38 PM


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yep downhill slide, however, we know that..

still holding
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theadder
Posted on: Apr 27 2011, 12:26 PM


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If as you say someone is accumulating why then is the share price sliding.

Accumulation = share price rising..????
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theadder
Posted on: Apr 18 2011, 07:51 PM


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From the latest edition of the Australian Defence Magazine
 
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theadder
Posted on: Apr 14 2011, 10:03 AM


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Global RNA Interference (RNAi) Market to Reach $4.04 Billion by 2017, According to a New Report by Global Industry Analysts, Inc.

http://www.benzinga.com/press-releases/11/...on-by-2017-acco

GIA announces the release of a comprehensive global report on RNA Interference markets. The global market for RNA Interference (RNAi) is forecast to reach $4.04 billion by the year 2017. The market for RNAi is driven by the increasing use of this technology as a research tool in functional genomics, that finds applications in drug discovery, target validation, and drug development, in addition to agricultural and plant biotechnology sectors. The market for RNA interference in the long-term is expected to be primarily driven by the development of RNAi-based therapeutics for various diseases.


San Jose, CA (Vocus/PRWEB) April 13, 2011

GIA announces the release of a comprehensive global report on RNA Interference markets. The global market for RNA Interference (RNAi) is forecast to reach $4.04 billion by the year 2017. The market for RNAi is driven by the increasing use of this technology as a research tool in functional genomics, that finds applications in drug discovery, target validation, and drug development, in addition to agricultural and plant biotechnology sectors. The market for RNA interference in the long-term is expected to be primarily driven by the development of RNAi-based therapeutics for various diseases.

RNA Interference (RNAi), a breakthrough biological phenomenon unraveled in the late 1990s, represents a promising technology with immense possibilities in the area of drug development for multiple indications. The effects of RNA interference have demonstrated the role of this process in regulation and silencing of specific endogenous gene activity as well as exogenous parasitic genes, and their genetic components inside a cell. The components (namely siRNA and miRNA) involved in this path breaking process are expected to become a new wide-ranging class of drugs, on the lines of monoclonal antibodies and small molecules, for the treatment of serious diseases such as cancer, viral infections, and genetic and neurological disorders. In addition to identifying druggable targets, RNAi could also be exploited in a number of applications, including research in functional genomics, disease diagnostics, and agriculture, among others. Over the years, the use of siRNA and miRNA in industries and academic institutions has witnessed a substantial growth.

The US and Europe together account for a lion's share of the global RNAi market, as stated by the new market research report on RNA Interference (RNAi). The US represents the single largest market. Europe constitutes the second largest as well as fastest growing market, growing at a compounded annual rate of 13.6% over the analysis period. Application-wise, RNAi in drug discovery and target validation, and RNAi reagents together dominate the RNAi market. However, in the coming years, RNAi reagent is expected to constitute the largest area of RNAi application. siRNA synthesis is expected to emerge as the fastest growing application area, with a CAGR of more than 15% over the analysis period.

Presently in the nascent stages, the RNAi industry is gaining ground in the therapeutics arena, with its most promising application being high-throughput screening. Given the role played by RNA interference in selective regulation and gene silencing, and the fact that it is a naturally occurring phenomenon in a number of organisms, RNAi-based therapeutics could potentially target a broad range of proteins, compared to a small class of proteins targeted by existing classes of drugs. Druggable targets for RNAi-based therapeutics could be easily identified using bioinformatics tools, in comparison to extensive lead optimization techniques required in the case of existing classes of drugs such as protein therapeutics and small molecules. The ease of identifying drug targets using bioinformatics is expected to drive the growth of RNAi-based therapeutics development. The first of the approved RNAi-based drugs are expected to foray into the therapeutics market in 2013. RNAi-based therapeutics, however, pose several challenges, the most prominent and still persistent being drug delivery. In addition, safety and efficacy, stability, and stimulation of non-specific immune response are also issues of concern with RNAi therapeutics. With an expected change in the patents and licenses scenario in the pharmaceutical industry, it is likely that more companies would explore RNAi technology to provide RNAi based products.

Major players profiled in the report include Alnylam Pharmaceuticals Inc., Benitec Limited, Bioneer Corp., Calando Pharmaceuticals Inc., Cenix BioScience GmbH, Devgen NV, Dharmacon Inc., Dicerna Pharmaceuticals Inc., Genesis Research & Development Corporation Limited, OPKO Health Inc., Polyplus-transfection SA, Quark Pharmaceuticals Inc., among others.

The research report titled "RNA Interference (RNAi): A Global Strategic Business Report" announced by Global Industry Analysts Inc., provides a comprehensive review of the RNA Interference, its applications, industry overview, industry outlook, regulatory approvals, technological innovations, recent industry activity, and profiles of major/niche global market participants. The report provides annual value sales estimates and projections for RNA Interference market for the years 2009 through 2017 for the following application areas - Drug Discovery and Target Validation, Reagents, and siRNA synthesis. Also, a seven-year (2003-2008) historic analysis is provided for additional perspective.

For more details about this comprehensive market research report, please visit – http://www.strategyr.com/RNA_interference_...rket_Report.asp



Read more: http://www.benzinga.com/press-releases/11/...o#ixzz1JS20HQ9e
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theadder
Posted on: Apr 8 2011, 06:39 PM


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Metal Storm Completes Private Placement

Brisbane, Australia – 8 April 2011: Metal Storm Limited.

Metal Storm advises that it has entered into a private share placement agreement to a total of $400,000 on similar terms to the August 2010 Rights Issue.

The Company will issue 40,000,000 shares to the investor at a purchase price of 1 cent per share.

Subject to shareholder approval, the Company will also issue 120,000,000 options with an exercise price of 1.5 cents. If shareholder approval is not obtained for the option issue, the Company will instead issue a further 26,666,667 shares to the investor.

The funds will be used to provide working capital to continue company operations and to progress the MAUL weapon and ammunition for delivery to customers.

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theadder
Posted on: Apr 7 2011, 09:52 AM


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Singapore's SciGen looks to sell Israel operations

http://www.globes.co.il/serveen/globes/doc...28&fid=1725
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theadder
Posted on: Apr 6 2011, 08:57 PM


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from ASD News..

http://www.asdnews.com/news/34618/Metal_St...n_Agreement.htm
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theadder
Posted on: Apr 4 2011, 12:33 PM


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http://www.biotechnologynews.net/storyview...storyid=2383915

Benitec cultivates

Cervical cancer research undertaken by scientists at the University of Queensland demonstrated the value of Benitec’s gene-silencing platform technology of DNA-directed ribonucleic acid interference (ddRNAi) to provide effective human therapeutics for cancer.

Results were published in the international scientific journal Cancer Gene Therapy this month after the scientists demonstrated cultured cervical cancer cells were rapidly killed when treated with ddRNAi in the form of two short hair pin RNAs linked together in one delivery vehicle.

Benitec chief executive Dr Peter French said it was pleasing to see further evidence being independently produced through Benitec’s ddRNAi technology.

The company hopes to partner its technology with major pharmaceutical companies to facilitate the introduction of ddRNAi-based therapeutics to market.
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theadder
Posted on: Apr 1 2011, 12:26 PM


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Mentioned today at the USPTO Daily Reexamination Center

Recently-Issued Reexamination Certificates

http://reexamcenter.com/2011/03/daily-reex...-march-30-2011/


Control # – 09/100,812
Patent # - 6,573,099
EX PARTE REEXAMINATION CERTIFICATE C1 (8071st)
Mar. 8, 2011
Synthetic Genes and Genetic Constructs Comprising Same I
Graham, Michael Wayne, St. Lucia (AU)
Commonwealth Scientific and Industrial Research Organization, Campbell, Australian Capital Territory (AU)
Claims 1-3 and 8-9 are cancelled.
Claims 4-7 and 10-22 are determined to be patentable as amended.
New claims 23-41 are added and determined to be patentable.

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theadder
Posted on: Mar 30 2011, 10:15 AM


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RNAi-based genetic screening: Past, Present & Future

http://www.nyas.org/Events/Detail.aspx?cid...66-d63fd17ee69c

RNA interference (RNAi) screening methodologies have revolutionized the fields of basic biological research, functional genomics, and drug development and discovery, providing complex and sometime challenging but yet extremely powerful tools to approach mechanisms underlying human disease and accelerate the development of treatments. This 1-day symposium will explore lessons, challenges, new discoveries and future directions in the development of RNAi screening technologies and delivery processes
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theadder
Posted on: Mar 30 2011, 09:57 AM


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Well worth reading..RNAi gets a mention in a big way

Where Indivual Investors Can Beat the Big Boys

http://news.goldseek.com/GoldSeek/1301410800.php

One of the more promising areas - one that's gone through a large period of hype and has now reached its realism phase - is RNA interference, or RNAi. A few years back, everybody was talking about RNAi being the next big therapy. It had its moment in the sun where there were 100 different companies all working in RNAi - it went through the unrealistic hype phase and is now getting down to brass tacks with a handful of much more obvious front-runners much closer to putting real therapies out to market.

After over a decade of progression from the lab to trials, today we're finally seeing real RNAi results in humans that allow us to treat certain genetic conditions and cure people of diseases that were otherwise completely untreatable prior to now. They are being successfully delivered, they are temporary and reversible unlike prior generations of genetic therapies that did not work nearly as well, and they are steadily marching toward market. But it's still not clear who the specific winners are going to be.






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theadder
Posted on: Mar 29 2011, 09:08 AM


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http://www.canadianbusiness.com/markets/ma...ntent=D9M8A30G2

March 28th 2011

Alnylam gets $10M from Takeda as part of RNAi partnership; Takeda made $20M payment last week


CAMBRIDGE, Mass. (AP) - Alnylam Pharmaceuticals Inc. said Monday it received $10 million from Japanese drugmaker Takeda Pharmaceutical Co. as part of the companies' collaboration on gene-silencing drugs.

Alnylam is transferring RNA interference drug technology to Takeda as part of the partnership, which began in May 2008. Alnylam said it has received $140 million in payments from Takeda over that time, including a $20 million payment last week. The partnership could be worth more than $1 billion in total and also includes options that would allow Alnylam to help market RNA drugs in the U.S. and split the U.S. profits with Takeda.

Drugs using RNA interference technology, or RNAi, are designed to shut down the proteins at the root of a disease or condition.

Shares of Alnylam fell 8 cents to $9.31 in morning trading.
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theadder
Posted on: Mar 24 2011, 11:40 AM


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http://www.bitlaw.com/source/37cfr/1_740.html
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theadder
Posted on: Mar 22 2011, 06:51 PM


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RNAi Therapeutics News and Research

http://www.news-medical.net/?tag=/RNAi+Therapeutics
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theadder
Posted on: Mar 22 2011, 09:29 AM


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Open Secrets, take a look around here and see the amounts being spent on lobbying..no wonder we are being
left behind

http://www.opensecrets.org/lobby/clientsum...m&year=2008

Top Lobbying Firms

http://www.opensecrets.org/lobby/top.php?indexType=l
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theadder
Posted on: Mar 22 2011, 09:19 AM


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http://chinahic.com/speakers.php
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theadder
Posted on: Mar 21 2011, 09:24 PM


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matches the share price....
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theadder
Posted on: Mar 21 2011, 11:10 AM


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Second US Clinical Study in HIV/AIDS Lymphoma Patients Using Benitec's ddRNAi Technology Announced

21 March 2011, Melbourne, Australia:
Benitec Limited (ASX:BLT), a world leader in RNA-based gene silencing for human therapeutics, is pleased to acknowledge that the City of Hope research hospital in Duarte, California is planning to initiate a second small Phase I/II study using Benitec's DNA-directed RNA interference (ddRNAi) technology in lymphoma patients carrying the HIV virus. The aim of the study is to optimize the treatment by modifying a range of clinical parameters.

From 2007 to 2010, Benitec funded the initial clinical development by the City of Hope of an RNA-based HIV/AIDS therapeutic molecule, one component of which is based on its ddRNAi technology – namely a short hairpin (sh)RNA construct targeted at a specific HIV gene. The novel ddRNAi-based product candidate was taken into a Phase I/II pilot human clinical trial and produced promising interim results in terms of safety and proof of feasibility. The data was published in Science Translational Medicine in June 2010.

Whilst this new study is not being funded by Benitec, it utilizes the same therapeutic molecule, and a successful outcome will be of significant benefit to Benitec as it will provide further clinical evidence of the potential of Benitec's proprietary technology for human therapeutics in general, and HIV/AIDS specifically.

Commenting on the news, Dr Peter French, CEO of Benitec, said: "We welcome the news of this second clinical study to explore ways to improve the performance of the RNA construct in the HIV/AIDS setting. Like the City of Hope, we believe that results of our work to date justified the further development of a ddRNAi-based cell therapy platform for HIV. Benitec is seeking to partner an HIV program based on ddRNAi to build on the initial promise of that work. This further study being undertaken by the City of Hope should assist in that aim."

Details of the new clinical study were reported in genomeweb
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theadder
Posted on: Mar 20 2011, 04:58 PM


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Great declaration Katich you deserved better from your fieldsmen.

He maketh the game and the slips fielders let him down.

Tassie should be two out.. thumbdown.gif

Now a third one dropped by the bat pad fieldsman..

Yes and guess who has dropped the catches Hughes and Jacques..
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theadder
Posted on: Mar 20 2011, 04:49 PM


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They have to get Tassie out so I don't think they can afford to bat tomorrow.

Will need the full day at them..Tassie will dig in as they don't have to win...

I do think Hughes and Jacques could have raised the tempo a lot sooner
they were only two out (Eight wickets left) and they were batting very slowly..
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theadder
Posted on: Mar 19 2011, 09:18 PM


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biggrin.gif



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theadder
Posted on: Mar 16 2011, 07:57 PM


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a pair of US patents granted yesterday..

Patent number... 7,906,660

title ~ Production of isoflavone derivatives

http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&u=%2Fnetahtml%2FPTO%2Fsearch-adv.htm&r=8&p=1&f=G&l=50&d=PTXT&S1=(20110315.PD.+AND+au.ASCO.)&OS=isd/3/15/2011+and+acn/au&RS=(ISD/20110315+AND+ACN/au
)

Patent number... 7,906,554
title ~ Combination chemotherapy compositions and methods

http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&u=%2Fnetahtml%2FPTO%2Fsearch-adv.htm&r=9&p=1&f=G&l=50&d=PTXT&S1=(20110315.PD.+AND+au.ASCO.)&OS=isd/3/15/2011+and+acn/au&RS=(ISD/20110315+AND+ACN/au
)
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theadder
Posted on: Mar 16 2011, 09:44 AM


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Welcome Vero I hope you enjoy the sharescene experience.

Looking forward to your contributions.

Good Luck with your investments
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theadder
Posted on: Mar 16 2011, 09:23 AM


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Alnylam Pharmaceuticals Reaches Settlement in Litigation Regarding Tuschl Patents

http://www.businesswire.com/news/home/2011...-Tuschl-Patents
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theadder
Posted on: Mar 15 2011, 09:04 AM


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Get it right plastic they have the '099 now going into the Ex Parte Reexamination

So if as you say they have the patent, what is going on????
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theadder
Posted on: Mar 14 2011, 01:39 PM


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Ex Parte Reexamination

http://reexamcenter.com/2009/09/ex-parte-reexamination/
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theadder
Posted on: Mar 14 2011, 01:38 PM


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Risks for Accused Infringers



The clearest risk for an accused infringer is that at least one asserted patent claim survives the reexamination process unamended and without any adverse prosecution history estoppels. The reexamination may allow the patent owner to have the CRU consider all of the prior art in the litigation and to present arguments and declarations that support patentability of the claims over this prior art. This could include, for instance, possible secondary (objective) considerations of non-obviousness that were not present when the claims were originally prosecuted.

An ex parte reexamination may also give the patent owner a significant advantage in dealing with the prior art because, once begun, the third party requester is excluded from the process, while the patent owner can interview the examiner.

Although the court can find a patent invalid even if it survives reexamination, most judges likely will defer to the presumed administrative expertise of the PTO, CRU, and BPAI.

Further, putting an asserted patent into reexamination could allow the patent owner to correct other defects in the patent, such as potentially ambiguous claim language, antecedent basis problems, or other perceived issues with the claims.

This is especially true with newly-issued patents where the potential for damages lies in the future, rather than with past damages. In the same vein, patent owners can also add claims during reexamination, provided that the added claims are not broader in scope than the original claims in reexamination. The added claims could strategically cover aspects of the accused infringing products not included in the issued claim set, although prohibitions against broadening amendments may bar such activity.

Finally, a reexamination request filed early on in the litigation could impact trial. This is especially true where the PTO decisions are favorable to patentability. However, as noted above, there are questions and concerns as to the admissibility of any non-final PTO action at trial.

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theadder
Posted on: Mar 12 2011, 12:12 PM


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Home / Committee Actions / Hearings

Mar 11 2011 11:30 AM

Counterproliferation Strategy for the Defense Threat Reduction Agency and Chemical Biological Defense Program
Subcommittee on Emerging Threats and Capabilities

Rayburn House Office Building - 2212

Permalink:


http://armedservices.house.gov/index.cfm/2...defense-program
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