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CUV, CLINUVEL PHARMACEUTICALS LIMITED
Epidan
post Posted: Sep 26 2019, 07:42 PM
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In Reply To: Clinhope's post @ Sep 26 2019, 10:07 AM

and that has any relevance to why clinuvel trades sideways for the last 6 weeks.
no, it doesnt,you are trying to sound smart talking about things that have nothing to do with Clinuvel pre FDA approval and the "shorters"

the share was overbought into the ASX200 inclusion, so it sold off and was shorted by algos down to were we are now.
they made 10/12 $ a share.
they are not idiots its an automated system.
they will have cycled themselves out of the position before the 6th.
Shorting has been part of trading markets for 200 years, its just a part of trading.

Educate yourself before blaming things you dont understand.
Enjoy!!!





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Artkatansclean
post Posted: Sep 26 2019, 07:17 PM
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In Reply To: Sherlock1123's post @ Sep 26 2019, 06:05 PM

Maybe 'cause some of you guys said that the approval or CRL could come earlier than 6th of October?...just guessin'...

 
Sherlock1123
post Posted: Sep 26 2019, 06:05 PM
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In Reply To: Dr Wally's post @ Sep 26 2019, 05:47 PM

That is the point: "OR they have insider FDA information of the outcome." If they would have, you would let the stock rise till October 1st/2nd, and watch it implode after the CRL, and then close your shorts.

If I somehow knew Clinuvel would not get approval I would not go short now. Why on earth would you do that and would you keep the SP low?



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Dr Wally
post Posted: Sep 26 2019, 05:47 PM
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He makes much sense and is very calm about the situation. Obviously he’s only been a holder for a few years if that. And seemingly hasn’t broken the golden rule of investing: putting all you eggs in the one basket. 🤓

I won’t be sad either “if FDA approval does not come”: I’ll be absolutely F ing irate!!!🤬

As has been stated here this shorting action is either stupidly not knowing or caring what a FDA approved Clinuvel means OR from history with regulators and previous form are betting that further delays are inevitable OR they have insider FDA information of the outcome.



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Wishing everyone the best of luck through these testing times. Hopefully we’ll all be getting back on track towards the end of this incredible year 2020.

Understand the reality of this unprecedented situation but don’t panic.

2020. Year of the germ!
 
mrdax
post Posted: Sep 26 2019, 05:47 PM
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In Reply To: sharelooker's post @ Sep 26 2019, 04:56 PM

Double, see sherlock

 
Sherlock1123
post Posted: Sep 26 2019, 05:45 PM
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In Reply To: sharelooker's post @ Sep 26 2019, 04:56 PM

There is a good point made in the vid regarding the shorts going on: it looks automated. If someone would have inside information that we will not get FDA approval it would make much more sense to let the stock rise till October 1st and go short, and watch it implode after October 6th, where you could close the shorts. It seems it is some stupid algorithm going mayhem. I assume the algorithm will get a major update after October 6th, although there might be a lack of money to fund the overhaul smile.gif


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sharelooker
post Posted: Sep 26 2019, 04:56 PM
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https://www.youtube.com/watch?v=3Yk9U-Gtb1Q


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Dr Wally
post Posted: Sep 26 2019, 11:58 AM
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But 1 example of why Scenesse MUST be approved in October ish and that further FDA delays are not acceptable.

FDA approved DHT (powerful male sex hormone) blocking drug for (possible, minimal, if at all) head hair loss many years ago. Must take daily for life.

Adverse side effects list is long and they are incredibly serious (multiple forms of cancer.)

“Finasteride was patented in **1984 and approved for medical use in 1992.** In 2016 it was the 75th most prescribed medication in the United States with more than 10 million prescriptions.”

Approved in approximately half the time it’s taken Scenesse to get to this point and still waiting.

“A 2016 meta-analysis found that sexual dysfunction, including erectile dysfunction, loss of libido, and reduced ejaculate, may occur in 3.4 to 15.8% of men treated with finasteride or dutasteride.[17] This adverse effect has been linked to lower quality of life and can cause stress in relationships.”

“There are case reports of persistent diminished libido or erectile dysfunction after stopping the drug and the FDA has updated the label to inform people of these reports.”

“The FDA has added a warning to 5α-reductase inhibitors concerning an increased risk of high-grade prostate cancer, as the treatment of BPH lowers PSA (prostate-specific antigen), which could mask the development of prostate cancer.”

“Although overall incidence of male breast cancer *in clinical trials* for finasteride 5 mg was not increased, there are *post-marketing* reports of breast cancer in association with its use.”

“Plus gynecomastia with 5α-reductase inhibitors is low at about 1.5%. “

“Depressive symptoms and suicidality have been reported.”

Did this extremely risky drug Finasteride face regulatory resistance and delays and other BS like Scenesse?

Scenesse =anti cancer. Adverse side effects list=0

Why wasn’t benign Scenesse FDA approved years ago.

Bad management? Really! You have got to be kidding me!





--------------------
Wishing everyone the best of luck through these testing times. Hopefully we’ll all be getting back on track towards the end of this incredible year 2020.

Understand the reality of this unprecedented situation but don’t panic.

2020. Year of the germ!
 
nipper
post Posted: Sep 26 2019, 11:21 AM
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In Reply To: PunkassDerm's post @ Sep 26 2019, 10:50 AM

QUOTE
regular Monte Carlo method or Monte Carlo integration, which are based on sequences of pseudorandom numbers.

In numerical analysis, the quasi-Monte Carlo method is a method for numerical integration and solving some other problems using low-discrepancy sequences (also called quasi-random sequences or sub-random sequences).
probably better to use QMC? (I mean, I'd hope there is some correlation between CEO pay scales. They cite others' to justify their own ... or at least the fancypants consultants do)



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"Every long-term security is nothing more than a claim on some expected future stream of cash that will be delivered into the hands of investors over time. For a given stream of expected future cash payments, the higher the price investors pay today for that stream of cash, the lower the long-term return they will achieve on their investment over time." - Dr John Hussman

"If I had even the slightest grasp upon my own faculties, I would not make essays, I would make decisions." ― Michel de Montaigne
 
PunkassDerm
post Posted: Sep 26 2019, 10:50 AM
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Well...it's just about time we go thermonuclear!
Frilly Frilly, Monte Carlo is everywhere


https://www.businessinsider.com/monte-carlo...-ceo-pay-2019-8


A mathematical technique originally developed to help build the atomic bomb is now used to figure out how much CEO pay packages are worth — like with Elon Musk


Executive compensation packages have gotten more complicated over time. To take one recent prominent example, Tesla CEO Elon Musk was "paid" around $2.3 billion last year by one valuation method, while actually receiving $0 in guaranteed value.

Indeed, some CEO pay plans are so complicated that a powerful mathematical technique originally developed to understand the behavior of neutrons in an atom bomb explosion is the most effective way to estimate what they are actually worth.

Monte Carlo methods, named for the famous casino, are a class of mathematical techniques for evaluating the possible outcomes of a complicated process that includes some random element. The basic idea in a Monte Carlo problem is to use a computer to simulate the random process many times — often thousands or millions of repetitions — and compare the various outcomes of those simulations.


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