Registered Members Login:
   
Forgotten Your Details? Click Here To Recover +
Welcome To The ShareCafe Community - Talk Shares And Take Stock With Smart Investors - New Here? Click To Register >

4910 Pages (Click to Jump) V   1 2 3 4 > »    
 
  
Reply to this topic

CUV, CLINUVEL PHARMACEUTICALS LIMITED
Dr Wally
post Posted: Yesterday, 11:46 PM
  Quote Post


Posts: 670
Thanks: 733


In Reply To: seeva222's post @ Yesterday, 09:45 AM

“”Sun tan threatens the coral reef””

I wonder what damage the year round slip slip slapping onto and into our porous skin is doing to humanity?

Now that the suncream devoted and long time advocating FDA has recently raised serious concerns about toxic chemicals easily entering and lingering in the blood stream, people might be on the look out for something that’s completely safe and 1000 times more effective.

When you look at the situation with a level head, it’s bad enough that adults are dealing with the constant application of these chemical soups but exposing young children and unborn fetuses to potent suncream chemicals is next level BS, at the same time demonising natural and disease preventing sunlight exposure is absolutely insane.

The concerns that were raised throughout the 2000s (by a few in the 90s) that were absolutely ignored and ridiculed because of the sacred cow status of suncream, might now be taken seriously.


https://www.ewg.org/sunscreen/report/the-tr...reen-chemicals/


“”2016- And though the published studies suggest that several chemical filters interact with human sex or thyroid hormones, there was not enough information about any of them to determine the potential risks to humans from hormone disruption.””

“”EWG has reviewed the existing data about human exposure and toxicity for the nine most commonly used sunscreen chemicals. The most worrisome is oxybenzone, which can cause allergic skin reactions (Rodriguez 2006). In lab studies, it is a weak estrogen and has potent anti-androgenic effects (Krause 2012, Ghazipura 2017).””

“”The Centers for Disease Control and Prevention routinely detect oxybenzone in more than 96 percent of Americans. Study participants who reported using sunscreen have higher oxybenzone exposures (Zamoiski 2015).””

“”In an evaluation of CDC-collected exposure data for American children, researchers found that adolescent boys with higher oxybenzone measurements had ***significantly lower total testosterone levels ***(Scinicariello 2016).””

“”According to the latest FDA sunscreens monograph, the agency needs further data to determine the GRASE status of oxybenzone, given that the “available literature … indicat[es] that oxybenzone is absorbed through the skin to a greater extent than previously understood and can lead to significant systemic exposure.… The significant systemic availability of oxybenzone … is a concern, among other reasons, because of questions raised in the published literature regarding the potential for endocrine activity.” Given the pervasiveness of oxybenzone exposures, we need further study to clarify its association with hormone disruption in children and adults.“”

“”EWG recommends consumers avoid sunscreens with oxybenzone. But sunscreen users are exposed to other active ingredients too. Margaret Schlumpf of the University of Zurich detected four other sunscreen filters along with oxybenzone in Swiss women’s breast milk, which suggests that the developing fetus and newborns may be exposed to these substances (Schlumpf 2008, Schlumpf 2010). She detected at least one sunscreen chemical in 85 percent of milk samples.””



--------------------
“” The discovery of the endogenous melanocortin agonists in the 1950s have resulted in sixty years of melanocortin ligand research.””

The never ending quest to have Afamelanotide (peptide) (SEMI) accepted for its potent ability to stimulate a natural photoprotective,cancer preventative, therapeutic “tan” was (SEMI) accomplished in 2019.

Regulator ignorance, bias, and stubborn resistance to Scenesse are the primary reasons behind this glacial journey. The evidence should be clear to all by now.
 
G dawg Delaney
post Posted: Yesterday, 09:56 PM
  Quote Post


Posts: 23
Thanks: 14


In Reply To: blackm3's post @ Feb 20 2020, 02:36 AM

QUOTE
there is 6500 VP patients in the Usa. Thats 3 times the Usa Epp market
QUOTE

I wonder seeings there are no safety concerns, whether Scenesse could be fast tracked for conditions like EPP. Seems like such a waste of time to delay for years longer an extremely likely therapy when safety is beyond doubt.


Said 'Thanks' for this post: blackm3  
 
Dr Wally
post Posted: Yesterday, 04:45 PM
  Quote Post


Posts: 670
Thanks: 733


In Reply To: Clinhope's post @ Yesterday, 12:47 PM

What! The worlds first systemic Photo protective, cancer preventative, long term proven absolutely safe Scenesse ?

The drug that stimulates, endogenous, 100% natural Eumelanin! shown to be greater then 99% effective at dissipating the negative effects of UVR over exposure!

Sorry thats all good BUT Scenesse has abuse potential soooo devastating it could cut skin cancer rates significantly within a couple of years. I know horrifying right!

What’s even more of a concern are the Billions of dollars at stake if ever Scenesse becomes widely available.

The potential for big industry suncream profits to be abused by Scenesse usage cannot be underestimated.



--------------------
“” The discovery of the endogenous melanocortin agonists in the 1950s have resulted in sixty years of melanocortin ligand research.””

The never ending quest to have Afamelanotide (peptide) (SEMI) accepted for its potent ability to stimulate a natural photoprotective,cancer preventative, therapeutic “tan” was (SEMI) accomplished in 2019.

Regulator ignorance, bias, and stubborn resistance to Scenesse are the primary reasons behind this glacial journey. The evidence should be clear to all by now.

Said 'Thanks' for this post: macgyver  G dawg Delaney  
 
Clinhope
post Posted: Yesterday, 12:47 PM
  Quote Post


Posts: 1,068
Thanks: 1241


In Reply To: seeva222's post @ Yesterday, 09:45 AM

Unfortunately the two best sunscreen ingredients, zinc and titanium oxide are the ones people (in general) dislike the most because they are what cause the whiteness when wearing sunscreen.

Shame there isn't something that can stimulate our bodies to produce a substance that is a result of hundreds of millions of years of evolution and is an extremely efficient skin protectant against both UVA and UVB rays....ohhhh wait a second!



--------------------
Member of the “ALL-IN” club 2018.

Said 'Thanks' for this post: waz  G dawg Delaney  
 
seeva222
post Posted: Yesterday, 09:45 AM
  Quote Post


Posts: 1,479
Thanks: 1679


Sun tan threatens the coral reef

https://www.instagram.com/tv/B8367tYB0ii/?i...id=zsar04mdx61o


Said 'Thanks' for this post: royco  G dawg Delaney  
 
Macquarie
post Posted: Feb 22 2020, 04:39 PM
  Quote Post


Posts: 27
Thanks: 38


In Reply To: macgyver's post @ Feb 22 2020, 09:32 AM

=investing in new trials and new indications for afamelanotide and cuv's other molecules.



--------------------
Check out my wikifolio (social Trading platform):
https://www.wikifolio.com/de/de/w/wfaloevera

Said 'Thanks' for this post: odi01  
 

sentifi.com

Share Cafe Sentifi Top themes and market attention on:


macgyver
post Posted: Feb 22 2020, 09:32 AM
  Quote Post


Posts: 737
Thanks: 696


In Reply To: odi01's post @ Feb 22 2020, 06:39 AM

Thanks for the post, I do have an issue with this line though...(a throwaway line by the author no doubt)

QUOTE
The company continues to reinvest its (now very high) profits in new drugs and the research into further fields of application for its current active ingredients.


Say what??

 
seeva222
post Posted: Feb 22 2020, 07:06 AM
  Quote Post


Posts: 1,479
Thanks: 1679


In Reply To: odi01's post @ Feb 22 2020, 06:39 AM

Thanks for the translation! Very helpful

 
odi01
post Posted: Feb 22 2020, 06:39 AM
  Quote Post


Posts: 737
Thanks: 1565


for a better world
Clinuvel is a biopharmaceutical company developing drugs for the treatment of a number of serious skin diseases. My Australian colleagues, among others, drew my attention to this company.
Its lead drug, SCENESSE, is used to treat erythropoietic protoporphyria (EPP). EPP is a rare, lifelong genetic disease characterized by severe skin intolerance to light, leading to unbearable pain, swelling and scarring. People living with EPP must avoid sunlight and often stay indoors. According to the company, approximately 10,000 people worldwide are affected by EPP.
SCENESSE is also used in the treatment of vitiligo, a common skin disease in which the skin's pigment-producing cells are missing. The company estimates that Vitiligo affects between 0.1 and 2% of the world's population (7.6 to 152 million people).
Clinuvel currently has a virtual monopoly. SCENESSE is the only drug approved for the treatment of EPP. The drug is currently approved in the EU and since October last year also in the USA.
The company continues to reinvest its (now very high) profits in new drugs and the research into further fields of application for its current active ingredients. Clinuvel could thus be able to help even more people with other diseases, some of which are serious and currently difficult to cure

https://m.onvista.de/news/3-wenig-bekannte-...-welt-330570623


Said 'Thanks' for this post: gerritbakker57  PortugueseMan  xlnja  San Diego  Farleap11  macgyver  waz  Verharven  G dawg Delaney  
 
bretto32
post Posted: Feb 21 2020, 04:50 AM
  Quote Post


Posts: 169
Thanks: 153


In Reply To: mrdax's post @ Feb 21 2020, 01:37 AM

I believe they did the same last year, it is in the days leading up to rare disease day.


Said 'Thanks' for this post: blackm3  
 
 


4910 Pages (Click to Jump) V   1 2 3 4 > » 

Back To Top Of Page
Reply to this topic


You agree through the use of ShareCafe, that you understand and accept the TERMS OF USE.


TERMS OF USE  -  CONTACT ADMIN  -  ADVERTISING