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CUV, CLINUVEL PHARMACEUTICALS LIMITED
investek
post Posted: Today, 01:12 AM
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In Reply To: FarmaZutical's post @ Yesterday, 07:34 PM

I’ve also been patiently waiting for the results of this trial (CUV011) and it is my personal belief that Wolgen is being very strategic with the duration of the trial/release of the full results.

I had a quick look back through a few of the past AGM presentations, see graphic below, I think it’s worth re-reading what Wolgen said years ago.

I think there are some other trials that never released full results, I haven’t completed an exhaustive review however I don’t recall ever seeing final results for CUV015 - Phase III Trial of CUV1647 in Polymorphic Light Eruption (PLE).

Clinical and regulatory progress:
- European and Australian Phase III trial (CUV015) preliminary results reported December 2009; see the announcement here
- Additional European Phase III trial (CUV032) commenced in Northern Hemisphere in spring of 2010
- Safety and efficacy shown in Phase II trials
- Program deferred

https://www.clinuvel.com/polymorphous-light-eruption-ple/

https://clinicaltrials.gov/ct2/show/NCT00472901
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seeva222
post Posted: Today, 12:59 AM
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If this does show progress for DNA repair what are the market implications?

Does this go to a broad-based market? Or will this just be used in high-risk situations?

Tx

 
waz
post Posted: Yesterday, 09:19 PM
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In Reply To: FarmaZutical's post @ Yesterday, 07:34 PM

This leads directly into the description of the recently granted patent where it states the compounds in particular benefit immunocompromised patients (in addition to the general public).

This was a Phase II trial. Would not be surprised therefore that at some stage, hopefully soon, results will be released. There are surely other trials where information was never released - this has been going on for 13 years. Dr Dennis Wtight key person in CUV1647 study.
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Attached File  Amended_description_with_annotations.pdf ( 46.12K ) Number of downloads: 11

 



Said 'Thanks' for this post: FarmaZutical  Alaaf  
 
FarmaZutical
post Posted: Yesterday, 07:34 PM
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One of the clinical trials that I have been most
interested in throughout the years is
CUV011 with 200 participants aimed to evaluate
Scenesse in AK/SCC in organ transplant recipients.

https://clinicaltrials.gov/ct2/show/NCT00829192

It had an end date in 2012 but results were never reported.
I’ve wondered for a long time if it was classic Clinuvel behavior
burying bad results or if there was indeed a strategic reason
for not reporting.

The principal investigator was / is Günther Hofbauer and in this article from
December, 2014 he states, that “studies are currently underway,” suggesting that
the trial was ongoing at that time.

https://serval.unil.ch/resource/serval:BIB_...87D78D.P001/REF

With the renewed focus on DNA repair and general protection against skin
cancers the AK/SCC OTR trial could be a centerpiece, I think.

Was it a failure, was it a success, was it still ongoing in 2014, is it still ongoing
today, was it finished and just waiting to be published at the right moment ?
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Said 'Thanks' for this post: PortugueseMan  IntiRaymi  waz  PunkassDerm  Alaaf  Texas T  
 
the near future
post Posted: Yesterday, 05:48 PM
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In Reply To: garthyd's post @ Yesterday, 04:58 PM

As you said, it can not last

SP is a joke at the moment, very cheap

Big new investor might join the party soon





Said 'Thanks' for this post: waz  
 
garthyd
post Posted: Yesterday, 04:58 PM
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In Reply To: the near future's post @ Yesterday, 04:36 PM

In only a month, our 12 month low will be $21......which its pretty unfathomable to think we could be at 12 month lows after FDA approval......It can't last.

 

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the near future
post Posted: Yesterday, 04:36 PM
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In Reply To: garthyd's post @ Yesterday, 03:16 PM

Nobody is selling, rather people are buying at this low sp price

the short sellers seems that they sold most of their shares, waiting to buy back

I hope we bottomed now, and short squeese will happen with any upcoming news





Said 'Thanks' for this post: waz  Alaaf  
 
garthyd
post Posted: Yesterday, 03:16 PM
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Gotta be one of our lowest volume trading days in months?

 
Fortescue Bullro...
post Posted: Yesterday, 11:55 AM
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Just ordered 2k at market. Very encouraged by all I am reading the last few days, and LHFUD receding in the rear view mirror. Thanks sharelooker, waz and all here.
Got them at 26.038.


Said 'Thanks' for this post: the near future  Alaaf  waz  
 
trisail
post Posted: Yesterday, 11:48 AM
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Friday 6th Dec on the ASX only 50,530 of the total volume of 164,852 shares sold were short sales. Some profit taking maybe?

 
 


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