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BS45
Posted on: Nov 22 2019, 10:21 AM


Group: Member
Posts: 13

that‘s my take on the agm as well.

after reading mr. wolgens company anouncement i asked myself why he/they concentrated so much on something they had never mentioned before in such an apodictic manner. they are building castles in the air instead of providing some reliable and down to earth timelines related to the existing indications.


“these new data, together with the existing label of systemic melanogenesis and systemic photoprotection, are of value to CLINUVEL and to its follow-on melanocortin products, and are the principal reason why most of management want to see the endgame of this Company“


my expectation was some clear words on their up to then favorised vitiligo trials right after fda approval (that is what they stated in their communiqué on october 17th - „we shall report on vitiligo shortly“) but now they are chasing another pig through the village before finishing what they started. this does not sound like a clear strategy (but they are bragging about their strategy).

i am just one of those fucking greedy investors (since 2005) but my wife suffers from vitiligo and i could not answer her question what the next steps are going to be (sorry, babe, forget about vitiligo, they found something better to suggest they are going to be the greatest skincare company on earth).


i never understood all the whining/whinging ( as we all know now) about the compensation package for the ceo. may he live to be a 123 years old and be the richest man in the cemetery but all the ends should not discourage him from reconsidering his strategy according to clear statements and timelines.






7 WORDS



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BS45
Posted on: Oct 9 2019, 03:13 AM


Group: Member
Posts: 13

do they know?
or not
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BS45
Posted on: Mar 17 2019, 09:43 AM


Group: Member
Posts: 13

they‘re still danish dynamite but too low-priced for dr. pj wolgen.
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BS45
Posted on: Mar 17 2019, 08:04 AM


Group: Member
Posts: 13

some say dr. philippe j.wolgen is french born but the majority refers to a dutch nationality. never heard of that he might be danish?
anyway we have to accept that he is an international man of mystery.
by the way ajax is a good choice for a dutch citizen. don‘t let him go for brøndby or kopenhagen, he might lose his ambition like homer j. simpson who was given the denver broncos instead of the dallas cowboys .
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BS45
Posted on: May 29 2018, 06:01 PM


Group: Member
Posts: 13





[i]
[/i]
[i]hie thee hither, that I may administer my implant under thine skin[/i]
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BS45
Posted on: Mar 18 2018, 10:32 PM


Group: Member
Posts: 13

nov 2013, after the resplit, = 0,093 € before (0,148 aud)


7000 EINLIEFERUNG 0,93902EUR 6.573,14 EUR 6,04 EUR +35.706,86 EUR

bought my first shares in 2005 at a price of 0,209EUR per share, an awfully long time ago..
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BS45
Posted on: Jun 30 2017, 01:28 AM


Group: Member
Posts: 13

oil = gas?
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BS45
Posted on: Jun 29 2017, 09:06 PM


Group: Member
Posts: 13

QUOTE
The Dutch have .... oil reserves similar to that of Iraq


that is fantastic news for the netherlands. the king oughta sheik hisbouti all day long.
[i][i]
where did you find this breaking news first?
[/i]
[/i]
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BS45
Posted on: May 7 2017, 10:05 PM


Group: Member
Posts: 13

from today`s "westfälische nachrichten" (german newspaper - online edition)

wn 07.05. 2017

google translation:

Yannik Hecht could enjoy the sunshine like everyone else - if the European Medicines Agency were not always putting stones in the way of the producers of an effective drug. The bodies of the "shading prickers" react immediately to burns on the sun's rays. The 20-year-old hopes that this will soon be over.
By Stefan Werding

Yannik Hecht can not be spoiled by the warm sunshine. Spring is pouring his nose through the door. It is one of the first warm days of the year. But the economics student from Münster looks out over the bright blue sky and says: "After the winter, such days as today are particularly hard."

The 20-year-old is a so-called "Schattenspringer". His body is allergic to certain sun rays. The pain is colossal. If he has not watched a few minutes and got a load of light, then his skin is irritated, burns and itches, swells also. Suncreams and pain relievers do not help cooling brings anything, touches become intolerable. That is why Yannik Hecht is not enthusiastic about a bright blue sky.
Long trousers, long-sleeved sweaters

In Germany there are about 400 known cases of EPP - the dark figure is about twice as high, because many people do not know why they have complaints. It is the blue portions of the light that they are emitting. Since there are also in lamps, sufferers can even sin in the house.

"From the Schattendasein the patient suddenly becomes everyday."

Professor Thorsten Marquardt on an effective drug

For Yannik Hecht's everyday life, this means that it is best to get outdoors only when the sun has completely disappeared. Otherwise, the 20-year-old will go from shadows to shadows, go faster and turn away from the sun as much as possible. He is wearing only long trousers and long-sleeved sweaters. He could also wear special coated sunshades. But they are too stupid.

When he goes to sea with his family on vacation, he only goes to the beach when the sun has disappeared behind the horizon. While the others sunbathe on the way to dinner, he enjoys the empty sea. "There is no annoyance," says Yannik. After all.
Barman4

Wait a few minutes in the sun to get burned hard. Photo: private

The illness was noticeable when Yannik's parents arrived early on the way to the holiday home in Denmark and waited in the sunshine to be admitted. In the night after, the boy, then a year and a half, had yelled and shouted. His skin was swollen. "Panic arose with us," says his mother Antje Voss today.
Means for the symptoms

The diagnosis is difficult, her pediatrician still did the pictures of the swollen skin, only when friends suggested the idea of ​​turning to a university clinic, the first time was the term EPP, the abbreviation for erythropoietic protoporphyria. Yannik was already two years older. The diagnosis was a "fright", after all the parents had already intuitively protected their child from sunlight. Voß says: "Children are often not believed. Doctors diagnose everything from solar energy to mental disorder. "

Thus, Yannik has been regularly sent out to school and kindergarten for sports because teachers and educators have not taken seriously the boy's advice - and his parents. "I've always tried to do as much as I can," says the student. That is why he looked for sports such as horseback riding and table tennis. They can also be operated in the hall.

The Bittere: There is a remedy for the symptoms of the disease. As early as 2014, the European Medicines Agency approved the drug afamelanotide. The Australian company Clinuvel has developed "Scenesse". The agent prevents light from entering the skin. Professor Thorsten Marquardt, specialist for metabolic diseases at the University Hospital of Münster, explains: "The situation for patients is dramatically better. From the Schattendasein, the patient suddenly becomes everyday. "97 percent of the patients were able to get into the sun for a long time after treatment - and without complaints.
Yannik, too, has two unique summers, in which he could move like others. Through a legal trick it was possible to get the medicine transplanted under the skin in Switzerland. "That was incomprehensible," says the mother. In the past two years, her son has matured so much that he has dared to move from Hamburg to Münster and live there alone. "Without this drug he would never have taken this step," she says.

Displeasure about European medicine agency
Now the health insurance companies do not want to pay the 25,000 euro expensive treatment. Marquardt wondered at the difficulties. The benefit of the drug was demonstrated in a highly qualified study and published in one of the most recognized medical journals. Nevertheless, the European Medicines Agency (EMA) has imposed so many conditions on the developers of the drug "Scenesse" that global market launch has become impossible.

"I've never seen anything like it before," says Marquardt. Instead, the company has to negotiate with individual clinics about the award of the drug. As a result, if "Scenesse" is permitted in Düsseldorf, it is by no means the case that it can be prescribed in Münster - although the medical use is undisputed. That is why Yannik was now at the Charité in Berlin. There he got the medicine.
EPP

A genetic defect is the cause of EPP. By this, the body of Yannik Hecht and other EPP patients produces too little ferrochelatase. This enzyme is involved in the formation of the red blood dye. If there is a lack of ferrochelatase, protoporphyrin accumulates in the body. This substance has the property of absorbing the energy of visible light and returning it as energy. The fabric is massively damaged. Professor Thorsten Marquardt, Head of the Department of Congenital Metabolic Diseases, who looks after patients like Yannik in the hospital, compares this with "internal burns".

The displeasure about the European Medicines Agency is so great that the patients and their relatives have already demonstrated in several cities to speed up the release of the drug. This has helped little so far. "I can not put into words how unjust this is," says Antje Voß. And in the face of the upcoming summer, Marquardt says, "This can not be the perfect year." Maybe next. And until then, Yannik Hecht hid from the sun. Good mood also goes without summer.
EPP_Berlin_31

brief summary (quotes from the article)
- The diagnosis is difficult. In Germany there are about 400 known cases of EPP - the dark figure is about twice as high
- Now the health insurance companies do not want to pay the 25,000 euro expensive treatment
- the European Medicines Agency (EMA) has imposed so many conditions on the developers of the drug "Scenesse" that global market
launch has become impossible
- the company has to negotiate with individual clinics about the award of the drug
- if "Scenesse" is permitted in Düsseldorf, it is by no means the case that it can be prescribed in Münster


maybe that´s why they say on epp deutschland that there are only a few treatments until now (epp deutschland)

also the article might not be completely up-to-date according to the price for the implant that should be well below the mentioned €25000.
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BS45
Posted on: Feb 10 2017, 10:02 AM


Group: Member
Posts: 13

tagesanzeiger.ch


www.tagesanzeiger.ch/wirtschaft/konjunktur/ein-monopol-das-schmerzt/story/21217227
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BS45
Posted on: Feb 10 2017, 09:57 AM


Group: Member
Posts: 13

the swiss have to swallow the pill

the swiss have to pay pw´s bill

tagesanzeiger.ch
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BS45
Posted on: Oct 14 2016, 09:35 PM


Group: Member
Posts: 13

apparently the larger statutory health insurance companies in germany (aok, barmer gek, techniker, dak, ikk classic, kkh) cover the costs of the therapy. effective date: 01.10.2016

arzneikompass.de

additional (prescription) charge: €10
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