Jump to content

theadder

Member
  • Posts

    5263
  • Joined

  • Last visited

Everything posted by theadder

  1. theadder

    UNS

    Hi there, From the USPTO yesterday a granted patent http://patft.uspto.gov/netacgi/nph-Parser?...u&RS=ACN/au United States Patent 9,050,415 Shetty , et al. June 9, 2015 Devices for targeted delivery of therapeutic implants Abstract An implant delivery syringe includes a barrel, a plunger assembly, and a barrel adapter. A barrel adapter mountable to a syringe barrel includes a barrel tip, needle retraction mechanism, needle assembly and stylet slidably disposed within the needle lumen. The needle retraction mechanism includes a biasing member, actuable locking arrangement and locking mechanism. When the actuable locking arrangement is actuated, the biasing member causes the needle to axially translate over the stylet during retraction to cause delivery of an implant to a target location. The stylet may be retracted following delivery. Methods of assembling, manufacturing, and using are also provided. Inventors: Shetty; Gautam N. (Pikesville, MD), Weir; Aaron M. (York Haven, PA), Brandt; Christian P. (York, PA), Castagna; Lou (Middletown, PA), Brenner; Tod H. (Pequea, PA)
  2. Hi PeterH, Haven't been around sharescene for awhile, however, an email alert popped up for EOS so here I am. How are you going???? Also a nice mention here a couple of hours ago from The World Today... http://www.abc.net.au/news/2014-08-26/elec...eal-wit/5697544 Good Luck to all holders... I do not hold EOS..
  3. When you see this side....then we will be where we belong.. Cowan, Watson, Kawaja, Clarke, Hussey, Warner, Payne, Pattison, Cummins, Starc & Lyon Pleny of othet good bowlers around like Johnson Cutting Siddle Harris Helfenhaus but batting is thin...
  4. hi wolv, now we have a good comparison... Tony Abbott is as good a performer in politics as Ricky Ponting was in captaining Australia.. Time for both to go, then going forward both teams performance will improve immensely.. This is IMHO... Bring on the cricket stuff the politics...
  5. come on now wolv...fess up... Yes he did screw Katich, no doubt about it it. The public took to him and I think he received a very valuable lesson about the Aussie ethics and learnt from it. He went from a "Hollywood sportsman" who the public detested, without doubt. He now comes over as a genuine Aussie sportsman in peak batting form and leading a average cricket team very successfully... I had my doubts about about him, however, one has to admit he seems to be the man.. Where is Jaytee when I need support???
  6. Indication is Patterson joins Cummins and is out for the rest of the season... Should see Starc in action now, surely????
  7. Hi frodo, I think you need to take into account Patterson will not bowl in this innings therefore Clarke needs time to get the South Africans out. It is very hot in Adelaide today and tomorrow so testing times in particular for fast bowlers. He has allowed time for them to rest and come back strong in short spells. When they are both resting the only front line bowler left is Lyons so there will be many overs bowled by part time bowlers. In these periods not many wickets would be expected. South Africa need a record last wicket score to win the match. Clarke needs time to do it and he has allowed the time for his bowlers to achieve it. If by some sort of miracle South Africa make the runs...I would be the first to say well done.
  8. Great double ton by Clarke, and centuries to Hussey and Warner. Fantastic EOD score with full credit to the above however, special mention to Warner who set the tempo early to initiate the onslaught. Great day for Michael Clarke and for Australian Cricket...bring on tomorrow... Sad to see Starc miss out again IMHO opinion a future star.. Look forward to the day when we see Paterson, Cummins and Starc as the fast bowling team...
  9. theadder

    MST

    Metal Storm looks to lock and load new debt restructure http://www.couriermail.com.au/business/met...4-1226511776060
  10. Looking into Callums' figures further..prior to this season for South Australia.. 65 matches 121 innings 35.33 Average 7 centuries & 25 half centuries... Now Adelaide Oval 32 matches 59 Innings Average 33.96 Only 1 ton in 59 innings on Adelaide Oval...the batmens paradise..
  11. As a staunch South Aussie who loves his cricket: Callum Ferguson looks to have all the goods but what a disappointment he has been. Averages in the 30s with half his games played on Adelaide Oval, the best batting wicket in the world. No consistancy in his batting, lovely technique but keeps getting out... Can not see him playing many tests for Australia...hope I'm wrong..
  12. Siddle couldn't bowl me....bring on Cummins, Pattison & Starc Then watch the South Africans jump around....but the old school tie boys will be in the 1st Test...nothing surer..
  13. theadder

    BLT

    Casey Analyst Forecasts Explosive Biotech Growth http://jutiagroup.com/20121011-casey-analy...biotech-growth/ It’ll start with a trickle, more than a flood. But make no mistake: RNAi, or temporary gene silencing through interference with the messenger RNA that signal cell behavior, looks to be one of the most important genetic treatment methodologies yet conceived. Genetics are at the root of just about every major chronic diseaseâ€â€ÂÂÂÂheart disease, cancer, diabetes. Gene silencing has serious promise with regard to controlling the root causes and predispositions for some of these maladies, instead of waging continuous battles against symptoms, as we do today.
  14. theadder

    MST

    RIP Arvet All the best Blue
  15. theadder

    MST

    One would think Metal Storm would need to find a "White Knight" ready to finance the company in the next couple of days...
  16. from ADM defence.. EOS and Hyundai join forces for remote weapon systems http://www.defencesuppliers.net.au/news/eo...-weapon-systems
  17. theadder

    MST

    hi olebluetwo' Haven't been to the other site for a few days so have been and had a look. Just the usual change of attitude on a week by week basis, depending on the post heading Commercialization = TRL9 preceded by lower TRLs as you go through the process. No technology is able to by pass the system. Some posters seem to think Metal Storm can get contracts with technology that is not mature.. No mention even of TRL 7 for Metal Storm so still years down the track, if they can survive..
  18. theadder

    MST

    Mission Payload Module update The purpose of this modification is to extend the proposal due date as identified in the SUMMARY OF CHANGES SECTION A - SOLICITATION/CONTRACT FORM The required response date/time has changed from 10-Jul-2012 03:30 PM to 24-Jul-2012 03:30 PM. https://www.fbo.gov/?s=opportunity&mode...re&_cview=1
  19. theadder

    BLT

    Spar Over Gene-Silencing Patent Is a Federal Case http://www.courthousenews.com/2012/06/20/47637.htm CHICAGO (CN) - Adispute over patent rights to a much-anticipated method of gene silencingshould not head to state court merely because one of co-owners to the patent isa state school, a federal judge ruled. The University ofUtah sued four private research institutes and officials with the University ofMassachusetts over patent rights to ribonucleic acid interference (RNAi), alsoknown as gene silencing. RNAi switches offa gene by preventing certain RNA molecules from producing proteins in the cell."It has great potential therapeutic value," U.S. District Judge PattiSaris explained. The University ofUtah's lawsuit seeks to name one of its faculty members, Dr. Brenda Bass, aseither the sole inventor or joint inventor of two RNAi-related patents, knownas Tuschl II patents for the first named investor, Dr. Thomas Tuschl. "The claimsof the Tuschl II patents are directed to methods of preparing a particular typeof double-stranded RNA molecule that can mediate RNAi," Saris wrote."The molecule has a '3' overhang,' a sequence of nucleotides on one end ofan RNA strand that hangs over the other RNA strand and make up adouble-stranded RNA molecule." Though the UMassofficials claimed that they have sovereign immunity as state actors, Sarisapplied an exception to that rule because, "unlike disputes over lakes,rivers, and state boundaries, a quarrel over patent rights does not implicatecore sovereign interests." The University ofUtah dropped Massachusetts as a party to the federal complaint to precludeexclusive jurisdiction in the state Supreme Court, and there is no supportbehind claims that the state is "an indispensible party," thedecision states. "A judgmentrendered in UMass' absence will not prejudice UMass or the other parties,"Saris wrote. "UMass' interests are well represented by the otherdefendants, internationally renowned research institutions and a university, aswell as the state officials themselves. Another dismissalattempt against the inventorship claims - this time from all of the defendants,including the Massachusetts Institute of Technology and Alnylam Pharmaceuticals- argued failure to state a claim. But Saris said"there are allegations of interaction between Dr. Bass and the namedinventors." The secondamended complaint "alleges that Dr. Bass published an article explainingthe capability to mediate RNAi in mammals with dsRNA fragments having a 3'overhang," she wrote. "The named inventors read her article, andincorporated her work. She also discussed her conception with the namedinventors at two conferences and over dinner. Federal Circuitcaselaw is clear that there is 'no bright-line standard' in determining jointinventorship," the decision concludes.
  20. http://www.lifescientist.com.au/article/42...file_bionomics/
  21. theadder

    BLT

    Benitec Biopharma moves towards human clinical studies for HIV/AIDS and Hepatitis C Wednesday, June 20, 2012 by Christine Feary http://www.proactiveinvestors.com.au/compa...nitec+Biopharmahttp://www.proactiveinvestors.com.au/compa...is-c-30331.html Benitec Biopharma (ASX: BLT) is progressing towards human clinical studies with the company’s multiple gene silencing technology programs. Trials of Benitec’s HIV/AIDS program have showed that the ddRNAi construct still expresses 3.5 years after the patient’s stem cells were transfected with a lentivirus construct. Benitec licensee Calimmune is targeting a clinical trial in HIV/AIDS patients in 2012, the first trial to use only ddRNAi constructs to target HIV in patients. In the United States, Benitec subsidiary Tacere Therapeutics has progressed the company’s Hepatitis C program to the point where an Investigational New Drug application is being prepared. Discussions with the US Food and Drug Administration are advanced. Already a large amount of clinical trial data has been manufactured, with a U.S. based clinical trial to begin as early as 2013. Meanwhile, pre-clinical testing of lead compounds for use in treating cancer-associated pain has been simplified, with all test species confirming strong activity against the target gene. Production of a material suitable for pre-clinical and clinical trials is now underway. Testing of Benitec’s other programs, which target areas such as non-small cell lung cancer, hepatitis B and oculopharyngeal muscular dystrophy, are also progressing well.
  22. theadder

    BLT

    Page 4... Benitec gets a mention New! dd-RNAi compound Gene silencing Benitec, Australia, Biomics, China Benitec.com Preclinical http://www.hepb.org/pdf/2012%20Spring_B%20Informed_Final.pdf
  23. theadder

    MST

    MLGLS Presentation at the recent Joint Armaments ConferenceTuesday14135orrison.pdf
  24. EOS announce new $25 million contract http://www.defencesuppliers.net.au/news/eo...llion-contract1
×
×
  • Create New...